Wen Chen1, Jian-Wen Jia, Jin-Rui Wang. 1. Department of Diagnostic Ultrasound, Peking University Third Hospital, 100083 Beijing, China. chenwen7989@yahoo.com
Abstract
OBJECTIVE: The purpose of this study was to describe the sonographic findings of soft tissue diffuse neurofibromas. METHODS: Seven soft tissue diffuse neurofibromas proven pathologically were retrospectively evaluated. Medical records and histologic examinations were reviewed, and sonograms were analyzed for the echogenicity, location, margin, and vascularity. RESULTS: All identified lesions were hyperechoic masses permeated by multiple interconnecting irregular hypoechoic tubular or nodular structures. All lesions were located in the subcutaneous fat zone, and all had poorly defined margins with adjacent normal subcutaneous fat. The margins between the lesions and the adjacent muscles were well defined in 5 and poorly defined in the other 2. The vascularity was extensive in 5 lesions and scarce in the other 2. CONCLUSIONS: Soft tissue diffuse neurofibromas have a characteristic sonographic appearance; therefore, sonography should be considered a useful tool in the initial screening of this disease.
OBJECTIVE: The purpose of this study was to describe the sonographic findings of soft tissue diffuse neurofibromas. METHODS: Seven soft tissue diffuse neurofibromas proven pathologically were retrospectively evaluated. Medical records and histologic examinations were reviewed, and sonograms were analyzed for the echogenicity, location, margin, and vascularity. RESULTS: All identified lesions were hyperechoic masses permeated by multiple interconnecting irregular hypoechoic tubular or nodular structures. All lesions were located in the subcutaneous fat zone, and all had poorly defined margins with adjacent normal subcutaneous fat. The margins between the lesions and the adjacent muscles were well defined in 5 and poorly defined in the other 2. The vascularity was extensive in 5 lesions and scarce in the other 2. CONCLUSIONS: Soft tissue diffuse neurofibromas have a characteristic sonographic appearance; therefore, sonography should be considered a useful tool in the initial screening of this disease.
Authors: David H Ballard; Parisa Mazaheri; Daniel C Oppenheimer; Meghan G Lubner; Christine O Menias; Perry J Pickhardt; William D Middleton; Vincent M Mellnick Journal: Radiographics Date: 2020-04-24 Impact factor: 5.333