Literature DB >> 17384021

Unsupervised segmentation of continuous genomic data.

Nathan Day1, Andrew Hemmaplardh, Robert E Thurman, John A Stamatoyannopoulos, William S Noble.   

Abstract

UNLABELLED: The advent of high-density, high-volume genomic data has created the need for tools to summarize large datasets at multiple scales. HMMSeg is a command-line utility for the scale-specific segmentation of continuous genomic data using hidden Markov models (HMMs). Scale specificity is achieved by an optional wavelet-based smoothing operation. HMMSeg is capable of handling multiple datasets simultaneously, rendering it ideal for integrative analysis of expression, phylogenetic and functional genomic data. AVAILABILITY: http://noble.gs.washington.edu/proj/hmmseg

Mesh:

Year:  2007        PMID: 17384021     DOI: 10.1093/bioinformatics/btm096

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  52 in total

1.  ChromHMM: automating chromatin-state discovery and characterization.

Authors:  Jason Ernst; Manolis Kellis
Journal:  Nat Methods       Date:  2012-02-28       Impact factor: 28.547

2.  H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome.

Authors:  Florian M Pauler; Mathew A Sloane; Ru Huang; Kakkad Regha; Martha V Koerner; Ido Tamir; Andreas Sommer; Andras Aszodi; Thomas Jenuwein; Denise P Barlow
Journal:  Genome Res       Date:  2008-12-01       Impact factor: 9.043

3.  Population analysis of large copy number variants and hotspots of human genetic disease.

Authors:  Andy Itsara; Gregory M Cooper; Carl Baker; Santhosh Girirajan; Jun Li; Devin Absher; Ronald M Krauss; Richard M Myers; Paul M Ridker; Daniel I Chasman; Heather Mefford; Phyllis Ying; Deborah A Nickerson; Evan E Eichler
Journal:  Am J Hum Genet       Date:  2009-01-22       Impact factor: 11.025

Review 4.  Making sense of cancer genomic data.

Authors:  Lynda Chin; William C Hahn; Gad Getz; Matthew Meyerson
Journal:  Genes Dev       Date:  2011-03-15       Impact factor: 11.361

5.  WAVELET-BASED GENETIC ASSOCIATION ANALYSIS OF FUNCTIONAL PHENOTYPES ARISING FROM HIGH-THROUGHPUT SEQUENCING ASSAYS.

Authors:  Heejung Shim; Matthew Stephens
Journal:  Ann Appl Stat       Date:  2015       Impact factor: 2.083

6.  Identifying and mapping cell-type-specific chromatin programming of gene expression.

Authors:  Troels T Marstrand; John D Storey
Journal:  Proc Natl Acad Sci U S A       Date:  2014-01-27       Impact factor: 11.205

7.  Simultaneous characterization of sense and antisense genomic processes by the double-stranded hidden Markov model.

Authors:  Julia Glas; Sebastian Dümcke; Benedikt Zacher; Don Poron; Julien Gagneur; Achim Tresch
Journal:  Nucleic Acids Res       Date:  2015-11-17       Impact factor: 16.971

8.  Genome-wide copy number variation in epilepsy: novel susceptibility loci in idiopathic generalized and focal epilepsies.

Authors:  Heather C Mefford; Hiltrud Muhle; Philipp Ostertag; Sarah von Spiczak; Karen Buysse; Carl Baker; Andre Franke; Alain Malafosse; Pierre Genton; Pierre Thomas; Christina A Gurnett; Stefan Schreiber; Alexander G Bassuk; Michel Guipponi; Ulrich Stephani; Ingo Helbig; Evan E Eichler
Journal:  PLoS Genet       Date:  2010-05-20       Impact factor: 5.917

9.  Discovery and characterization of chromatin states for systematic annotation of the human genome.

Authors:  Jason Ernst; Manolis Kellis
Journal:  Nat Biotechnol       Date:  2010-07-25       Impact factor: 54.908

10.  A varying threshold method for ChIP peak-calling using multiple sources of information.

Authors:  Kuan-Bei Chen; Yu Zhang
Journal:  Bioinformatics       Date:  2010-09-15       Impact factor: 6.937

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.