| Literature DB >> 17383023 |
Xing-Long Gu1, Yan-Gang Sun, Long-Chuan Yu.
Abstract
The hindpaw withdrawal latencies (HWLs) to noxious thermal and mechanical stimulation increased significantly after intra-hypothalamic arcuate nucleus (ARC) injection of galanin in mononeuropathic rats, while intra-ARC injection of the putative antagonist of galanin receptors markedly reduced the HWLs. The number of galaninergic neurons in the ARC increased in rats with mononeuropathy than that in normal rats. The results demonstrated that both endogenous and exogenous galanin were involved in the regulation of nociception in the ARC of rats with peripheral nerve injury.Entities:
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Year: 2007 PMID： 17383023 DOI： 10.1016/j.bbr.2007.02.033
Source DB: PubMed Journal: Behav Brain Res ISSN： 0166-4328 Impact factor: 3.332