Literature DB >> 1738209

Mutational analysis of conserved N-linked glycosylation sites of human immunodeficiency virus type 1 gp41.

W R Lee1, X F Yu, W J Syu, M Essex, T H Lee.   

Abstract

Amino acid substitutions were introduced into four conserved N-linked glycosylation sites of the human immunodeficiency virus type 1 envelope transmembrane glycoprotein, gp41, to alter the canonical N-linked glycosylation sequences. One altered site produced a severe impairment of viral infectivity, which raises the possibility that N-linked sugars at this site may have an important role in the human immunodeficiency virus type 1 life cycle.

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Year:  1992        PMID： 1738209      PMCID： PMC240944     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  23 in total

1.  Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine.

Authors:  B D Walker; M Kowalski; W C Goh; K Kozarsky; M Krieger; C Rosen; L Rohrschneider; W A Haseltine; J Sodroski
Journal:  Proc Natl Acad Sci U S A       Date:  1987-11       Impact factor: 11.205

2.  Interaction between the human T-cell lymphotropic virus type IIIB envelope glycoprotein gp120 and the surface antigen CD4: role of carbohydrate in binding and cell fusion.

Authors:  T J Matthews; K J Weinhold; H K Lyerly; A J Langlois; H Wigzell; D P Bolognesi
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

3.  A general model for the transmembrane proteins of HIV and other retroviruses.

Authors:  W R Gallaher; J M Ball; R F Garry; M C Griffin; R C Montelaro
Journal:  AIDS Res Hum Retroviruses       Date:  1989-08       Impact factor: 2.205

4.  Expression of membrane-associated and secreted variants of gp160 of human immunodeficiency virus type 1 in vitro and in continuous cell lines.

Authors:  P W Berman; W M Nunes; O K Haffar
Journal:  J Virol       Date:  1988-09       Impact factor: 5.103

5.  Nucleotide sequence of the AIDS virus, LAV.

Authors:  S Wain-Hobson; P Sonigo; O Danos; S Cole; M Alizon
Journal:  Cell       Date:  1985-01       Impact factor: 41.582

6.  Antibody responses in early human immunodeficiency virus type 1 infection in hemophiliacs.

Authors:  M J Chou; T H Lee; A Hatzakis; T Mandalaki; M F McLane; M Essex
Journal:  J Infect Dis       Date:  1988-04       Impact factor: 5.226

7.  Role of conserved gp41 cysteine residues in the processing of human immunodeficiency virus envelope precursor and viral infectivity.

Authors:  W J Syu; W R Lee; B Du; Q C Yu; M Essex; T H Lee
Journal:  J Virol       Date:  1991-11       Impact factor: 5.103

8.  A naturally immunogenic virion-associated protein specific for HIV-2 and SIV.

Authors:  X F Yu; S Ito; M Essex; T H Lee
Journal:  Nature       Date:  1988-09-15       Impact factor: 49.962

9.  Attenuation of human immunodeficiency virus type 1 cytopathic effect by a mutation affecting the transmembrane envelope glycoprotein.

Authors:  M Kowalski; L Bergeron; T Dorfman; W Haseltine; J Sodroski
Journal:  J Virol       Date:  1991-01       Impact factor: 5.103

10.  Processing and secretion of envelope glycoproteins of human immunodeficiency virus type 1 in the presence of trimming glucosidase inhibitor deoxynojirimycin.

Authors:  R Pal; V S Kalyanaraman; G M Hoke; M G Sarngadharan
Journal:  Intervirology       Date:  1989       Impact factor: 1.763
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  21 in total

1.  Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa.

Authors:  Ming Li; Jesus F Salazar-Gonzalez; Cynthia A Derdeyn; Lynn Morris; Carolyn Williamson; James E Robinson; Julie M Decker; Yingying Li; Maria G Salazar; Victoria R Polonis; Koleka Mlisana; Salim Abdool Karim; Kunxue Hong; Kelli M Greene; Miroslawa Bilska; Jintao Zhou; Susan Allen; Elwyn Chomba; Joseph Mulenga; Cheswa Vwalika; Feng Gao; Ming Zhang; Bette T M Korber; Eric Hunter; Beatrice H Hahn; David C Montefiori
Journal:  J Virol       Date:  2006-09-13       Impact factor: 5.103

2.  Conserved, N-linked carbohydrates of human immunodeficiency virus type 1 gp41 are largely dispensable for viral replication.

Authors:  W E Johnson; J M Sauvron; R C Desrosiers
Journal:  J Virol       Date:  2001-12       Impact factor: 5.103

3.  Alternate pathways of secretion of simian immunodeficiency virus envelope glycoproteins.

Authors:  C P Spies; R W Compans
Journal:  J Virol       Date:  1993-11       Impact factor: 5.103

4.  Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120.

Authors:  M T Esser; T Mori; I Mondor; Q J Sattentau; B Dey; E A Berger; M R Boyd; J D Lifson
Journal:  J Virol       Date:  1999-05       Impact factor: 5.103

5.  Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies.

Authors:  Ming Li; Feng Gao; John R Mascola; Leonidas Stamatatos; Victoria R Polonis; Marguerite Koutsoukos; Gerald Voss; Paul Goepfert; Peter Gilbert; Kelli M Greene; Miroslawa Bilska; Denise L Kothe; Jesus F Salazar-Gonzalez; Xiping Wei; Julie M Decker; Beatrice H Hahn; David C Montefiori
Journal:  J Virol       Date:  2005-08       Impact factor: 5.103

6.  Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.

Authors:  M B Zwick; A F Labrijn; M Wang; C Spenlehauer; E O Saphire; J M Binley; J P Moore; G Stiegler; H Katinger; D R Burton; P W Parren
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103

7.  Genomic cloning and complete sequence analysis of a highly divergent African human immunodeficiency virus isolate.

Authors:  M Vanden Haesevelde; J L Decourt; R J De Leys; B Vanderborght; G van der Groen; H van Heuverswijn; E Saman
Journal:  J Virol       Date:  1994-03       Impact factor: 5.103

8.  Functional role of the glycan cluster of the human immunodeficiency virus type 1 transmembrane glycoprotein (gp41) ectodomain.

Authors:  E Fenouillet; I Jones; B Powell; D Schmitt; M P Kieny; J C Gluckman
Journal:  J Virol       Date:  1993-01       Impact factor: 5.103

9.  Effects of amino acid changes in the extracellular domain of the human immunodeficiency virus type 1 gp41 envelope glycoprotein.

Authors:  J Cao; L Bergeron; E Helseth; M Thali; H Repke; J Sodroski
Journal:  J Virol       Date:  1993-05       Impact factor: 5.103

10.  Human immunodeficiency virus type 1 envelope glycoprotein is modified by O-linked oligosaccharides.

Authors:  H B Bernstein; S P Tucker; E Hunter; J S Schutzbach; R W Compans
Journal:  J Virol       Date:  1994-01       Impact factor: 5.103
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