| Literature DB >> 17381284 |
D J Patel1, J-B Ma, Y-R Yuan, K Ye, Y Pei, V Kuryavyi, L Malinina, G Meister, T Tuschl.
Abstract
We outline structure-function contributions from our laboratories on protein-RNA recognition events that monitor siRNA length, 5 -phosphate and 2-nucleotide 3 overhangs, as well as the architecture of Argonaute, its externally bound siRNA complex, and Argonaute-based models involving guide-strand-mediated mRNA binding, cleavage, and release.Entities:
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Year: 2006 PMID： 17381284 PMCID： PMC4689314 DOI： 10.1101/sqb.2006.71.053
Source DB: PubMed Journal: Cold Spring Harb Symp Quant Biol ISSN： 0091-7451