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Literature DB >> 17377672

Photochromically-controlled, reversibly-activated MRI and optical contrast agent.

Abstract

The contrast agent which tethers a spiropyran group to a Gd-DO3A moiety has higher relaxivity and fluorescence intensity in the dark; the relaxivity and fluorescence intensity decrease after irradiation with visible light.

Entities: Chemical

Mesh：

Substances：
Contrast Media

Year: 2007 PMID： 17377672 PMCID： PMC2556594 DOI： 10.1039/b616991k

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

13 in total

1. In vivo visualization of gene expression using magnetic resonance imaging.

Authors: A Y Louie; M M Hüber; E T Ahrens; U Rothbächer; R Moats; R E Jacobs; S E Fraser; T J Meade
Journal: Nat Biotechnol Date: 2000-03 Impact factor: 54.908

Review 2. Lariat ether receptor systems show experimental evidence for alkali metal cation-pi interactions.

Authors: George W Gokel; Leonard J Barbour; Riccardo Ferdani; Jiaxin Hu
Journal: Acc Chem Res Date: 2002-10 Impact factor: 22.384

Review 3. Molecular imaging: The latest generation of contrast agents and tissue characterization techniques.

Authors: Francis G Blankenberg
Journal: J Cell Biochem Date: 2003-10-15 Impact factor: 4.429

4. Receptor mediated uptake of a radiolabeled contrast agent sensitive to beta-galactosidase activity.

Authors: Mian M Alauddin; Angelique Y Louie; Antranik Shahinian; Thomas J Meade; Peter S Conti
Journal: Nucl Med Biol Date: 2003-04 Impact factor: 2.408

Review 5. Tissue-specific MR contrast agents.

Authors: Hanns-Joachim Weinmann; Wolfgang Ebert; Bernd Misselwitz; Heribert Schmitt-Willich
Journal: Eur J Radiol Date: 2003-04 Impact factor: 3.528

6. Alteration of electronic relaxation in MR contrast agents through de-novo ligand design.

Authors: R B Shukla; K Kumar; R Weber; X Zhang; M Tweedle
Journal: Acta Radiol Suppl Date: 1997

7. Spiropyran-based photochromic polymer nanoparticles with optically switchable luminescence.

Authors: Ming-Qiang Zhu; Linyong Zhu; Jason J Han; Wuwei Wu; James K Hurst; Alexander D Q Li
Journal: J Am Chem Soc Date: 2006-04-05 Impact factor: 15.419

8. Family of site-selective molecular optical switches.

Authors: Tomoyo Sakata; Yuling Yan; Gerard Marriott
Journal: J Org Chem Date: 2005-03-18 Impact factor: 4.354

9. Synthesis and photochromism of spirobenzopyran derivatives bearing an oxymethylcrown ether moiety: metal ion-induced switching between positive and negative photochromisms.

Authors: M Tanaka; M Nakamura; M A Salhin; T Ikeda; K Kamada; H Ando; Y Shibutani; K Kimura
Journal: J Org Chem Date: 2001-03-09 Impact factor: 4.354

10. Firefly luciferase gene: structure and expression in mammalian cells.

Authors: J R de Wet; K V Wood; M DeLuca; D R Helinski; S Subramani
Journal: Mol Cell Biol Date: 1987-02 Impact factor: 4.272

11 in total

1. Design, synthesis, and evaluation of 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid derived, redox-sensitive contrast agents for magnetic resonance imaging.

Authors: Natarajan Raghunand; Gerald P Guntle; Vijay Gokhale; Gary S Nichol; Eugene A Mash; Bhumasamudram Jagadish
Journal: J Med Chem Date: 2010-09-23 Impact factor: 7.446

Photochromically-controlled, reversibly-activated MRI and optical contrast agent.

1. In vivo visualization of gene expression using magnetic resonance imaging.

Review 2. Lariat ether receptor systems show experimental evidence for alkali metal cation-pi interactions.

Review 3. Molecular imaging: The latest generation of contrast agents and tissue characterization techniques.

4. Receptor mediated uptake of a radiolabeled contrast agent sensitive to beta-galactosidase activity.

Review 5. Tissue-specific MR contrast agents.

6. Alteration of electronic relaxation in MR contrast agents through de-novo ligand design.

7. Spiropyran-based photochromic polymer nanoparticles with optically switchable luminescence.

8. Family of site-selective molecular optical switches.

9. Synthesis and photochromism of spirobenzopyran derivatives bearing an oxymethylcrown ether moiety: metal ion-induced switching between positive and negative photochromisms.

10. Firefly luciferase gene: structure and expression in mammalian cells.

1. Design, synthesis, and evaluation of 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid derived, redox-sensitive contrast agents for magnetic resonance imaging.

2. Multimodal magnetic-resonance/optical-imaging contrast agent sensitive to NADH.

Review 3. Multimodality imaging probes: design and challenges.

4. Gadolinium-encapsulating iron oxide nanoprobe as activatable NMR/MRI contrast agent.

5. Receptor-targeted iron oxide nanoparticles for molecular MR imaging of inflamed atherosclerotic plaques.

Review 6. Strategies for the development of gadolinium-based 'q'-activatable MRI contrast agents.

7. Synthesis and characterization of a redox- and light-sensitive MRI contrast agent.

Review 8. Environmentally responsive MRI contrast agents.

Review 9. Redox- and hypoxia-responsive MRI contrast agents.

10. Reversible low-light induced photoswitching of crowned spiropyran-DO3A complexed with gadolinium(III) ions.