Literature DB >> 17377526

Metaplasia and transdifferentiation: from pure biology to the clinic.

Jonathan M W Slack1.   

Abstract

Transformations from one tissue type to another make up a well established set of phenomena that can be explained by the principles of developmental biology. Although these phenomena might be rare in nature, we can now imagine the possibility of deliberately reprogramming cells from one tissue type to another by manipulating the expression of transcription factors. This approach could generate new therapies for many human diseases.

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Year:  2007        PMID: 17377526     DOI: 10.1038/nrm2146

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN: 1471-0072            Impact factor:   94.444


  96 in total

Review 1.  Myeloid cells and lymphangiogenesis.

Authors:  Adrian Zumsteg; Gerhard Christofori
Journal:  Cold Spring Harb Perspect Med       Date:  2012-06       Impact factor: 6.915

Review 2.  Adult pancreatic alpha-cells: a new source of cells for beta-cell regeneration.

Authors:  Cheng-Ho Chung; Fred Levine
Journal:  Rev Diabet Stud       Date:  2010-08-10

Review 3.  Cdx genes, inflammation, and the pathogenesis of intestinal metaplasia.

Authors:  Douglas B Stairs; Jianping Kong; John P Lynch
Journal:  Prog Mol Biol Transl Sci       Date:  2010       Impact factor: 3.622

Review 4.  Engineering Cell Fate for Tissue Regeneration by In Vivo Transdifferentiation.

Authors:  I de Lázaro; K Kostarelos
Journal:  Stem Cell Rev Rep       Date:  2016-02       Impact factor: 5.739

Review 5.  Barrett's Esophagus: A Comprehensive and Contemporary Review for Pathologists.

Authors:  Bita V Naini; Rhonda F Souza; Robert D Odze
Journal:  Am J Surg Pathol       Date:  2016-05       Impact factor: 6.394

6.  Transforming growth factor-beta signaling network regulates plasticity and lineage commitment of lung cancer cells.

Authors:  I Ischenko; J Liu; O Petrenko; M J Hayman
Journal:  Cell Death Differ       Date:  2014-03-28       Impact factor: 15.828

7.  Stage specific reprogramming of mouse embryo liver cells to a beta cell-like phenotype.

Authors:  Ying Yang; Ersin Akinci; James R Dutton; Anannya Banga; Jonathan M W Slack
Journal:  Mech Dev       Date:  2013-08-30       Impact factor: 1.882

Review 8.  Metaplasia: tissue injury adaptation and a precursor to the dysplasia-cancer sequence.

Authors:  Veronique Giroux; Anil K Rustgi
Journal:  Nat Rev Cancer       Date:  2017-09-01       Impact factor: 60.716

9.  Lineage Plasticity in Cancer Progression and Treatment.

Authors:  Clémentine Le Magnen; Michael M Shen; Cory Abate-Shen
Journal:  Annu Rev Cancer Biol       Date:  2017-12-01

10.  Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A.

Authors:  Chinh Q Hoang; Michael A Hale; Ana C Azevedo-Pouly; Hans P Elsässer; Tye G Deering; Spencer G Willet; Fong C Pan; Mark A Magnuson; Christopher V E Wright; Galvin H Swift; Raymond J MacDonald
Journal:  Mol Cell Biol       Date:  2016-11-28       Impact factor: 4.272

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