Literature DB >> 17377203

Role of nuclear factor kappaB in the central nervous system.

Robert Małek1, Kinga K Borowicz, Małgorzata Jargiełło, Staniław J Czuczwar.   

Abstract

The aim of this review was to assemble current literature data on nuclear factor kappa B (NF-kappaB). Many authors believe that NF-kappaB, a transcription factor, has essential influence on the regulation of numerous genes in the organism. In this review, we have focused on the role of NF-kappaB and its target genes in the central nervous system functioning. Unfortunately, the contribution of NF-kappaB to neuroprotection or to neurodegeneration is not clear, yet. Therefore, its exact role in these processes and potential applications in pharmacology are still to be determined.

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Year:  2007        PMID： 17377203

Source DB:  PubMed          Journal:  Pharmacol Rep        ISSN： 1734-1140            Impact factor:   3.024


  23 in total

Review 1.  Immunoproteasomes: structure, function, and antigen presentation.

Authors:  Deborah A Ferrington; Dale S Gregerson
Journal:  Prog Mol Biol Transl Sci       Date:  2012       Impact factor: 3.622

2.  Protective effect of naringenin in experimental ischemic stroke: down-regulated NOD2, RIP2, NF-κB, MMP-9 and up-regulated claudin-5 expression.

Authors:  Xue Bai; Xiangjian Zhang; Linyu Chen; Jian Zhang; Lan Zhang; Xumeng Zhao; Ting Zhao; Yuan Zhao
Journal:  Neurochem Res       Date:  2014-05-20       Impact factor: 3.996

3.  NF-κB subunits are differentially distributed in cells of lumbar dorsal root ganglia in naïve and diabetic rats.

Authors:  L N Berti-Mattera; B Larkin; Z Hourmouzis; T S Kern; R E Siegel
Journal:  Neurosci Lett       Date:  2010-12-16       Impact factor: 3.046

Review 4.  The Janus-faced effects of hypoxia on astrocyte function.

Authors:  Grace Vangeison; David A Rempe
Journal:  Neuroscientist       Date:  2009-12       Impact factor: 7.519

5.  Ankyrin-rich membrane spanning protein plays a critical role in nuclear factor-kappa B signaling.

Authors:  Lynn F Sniderhan; Angela Stout; Yuanan Lu; Moses V Chao; Sanjay B Maggirwar
Journal:  Mol Cell Neurosci       Date:  2008-04-16       Impact factor: 4.314

6.  Pretreatment by evodiamine is neuroprotective in cerebral ischemia: up-regulated pAkt, pGSK3β, down-regulated NF-κB expression, and ameliorated BBB permeability.

Authors:  Ting Zhao; Xiangjian Zhang; Yuan Zhao; Lan Zhang; Xue Bai; Jian Zhang; Xumeng Zhao; Linyu Chen; Lina Wang; Lili Cui
Journal:  Neurochem Res       Date:  2014-06-12       Impact factor: 3.996

Review 7.  Making the brain glow: in vivo bioluminescence imaging to study neurodegeneration.

Authors:  Katja Hochgräfe; Eva-Maria Mandelkow
Journal:  Mol Neurobiol       Date:  2012-11-29       Impact factor: 5.590

8.  Rosmarinic acid protects against experimental diabetes with cerebral ischemia: relation to inflammation response.

Authors:  Haiyun Luan; Zechun Kan; Yong Xu; Changjun Lv; Wanglin Jiang
Journal:  J Neuroinflammation       Date:  2013-02-17       Impact factor: 8.322

9.  Immunoproteasome deficiency modifies the alternative pathway of NFκB signaling.

Authors:  Marcela Maldonado; Rebecca J Kapphahn; Marcia R Terluk; Neal D Heuss; Ching Yuan; Dale S Gregerson; Deborah A Ferrington
Journal:  PLoS One       Date:  2013-02-14       Impact factor: 3.240

10.  Parthenolide is neuroprotective in rat experimental stroke model: downregulating NF-κB, phospho-p38MAPK, and caspase-1 and ameliorating BBB permeability.

Authors:  Lipeng Dong; Huimin Qiao; Xiangjian Zhang; Xiaolin Zhang; Chaohui Wang; Lina Wang; Lili Cui; Jingru Zhao; Yinxue Xing; Yanhua Li; Zongjie Liu; Chunhua Zhu
Journal:  Mediators Inflamm       Date:  2013-07-11       Impact factor: 4.711
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