Jie Zhang1, Wei Zhang, Bin Li. 1. Department of Anesthesiology, The First Affiliated Hospital of ZhengZhou University, No. 1 East-JianShe Road, ZhengZhou 450052, China. joannyzh@hotmail.com
Abstract
BACKGROUND: We evaluated sevoflurane requirements during combined general-epidural anesthesia with different concentration of ropivacaine. METHODS:Fifty-six patients were randomly divided into three groups to epidurally receive saline, 0.2% ropivacaine or 1% ropivacaine. Sevoflurane concentration was adjusted to maintain certain anesthesia depth. BIS values and end-tidal sevoflurane concentrations were recorded at time points of pre-intubation and 5 min, 10 min, 15 min, 20 min, 25 min, 30 min after intubation. RESULTS: End-tidal sevoflurane was significantly lower in the group receiving higher concentration of sevoflurane. CONCLUSIONS:Epidural anesthesia can decrease sevoflurane requirements to a larger extent when a higher concentration of ropivacaine was applied.
RCT Entities:
BACKGROUND: We evaluated sevoflurane requirements during combined general-epidural anesthesia with different concentration of ropivacaine. METHODS: Fifty-six patients were randomly divided into three groups to epidurally receive saline, 0.2% ropivacaine or 1% ropivacaine. Sevoflurane concentration was adjusted to maintain certain anesthesia depth. BIS values and end-tidal sevoflurane concentrations were recorded at time points of pre-intubation and 5 min, 10 min, 15 min, 20 min, 25 min, 30 min after intubation. RESULTS: End-tidal sevoflurane was significantly lower in the group receiving higher concentration of sevoflurane. CONCLUSIONS: Epidural anesthesia can decrease sevoflurane requirements to a larger extent when a higher concentration of ropivacaine was applied.
Authors: Serdar Kokulu; Elif Doğan Bakı; Emre Kaçar; Ahmet Bal; Hasan Şenay; Kübra Demir Üstün; Sezgin Yılmaz; Yüksel Ela; Remziye Gül Sıvacı Journal: Med Sci Monit Date: 2014-12-23
Authors: Liyan Zhao; Yonghai Zhang; Fan Yang; Di Zhu; Ningkang Li; Li Zhao; Na Li; Jianqiang Yu; Hanxiang Ma Journal: Mol Med Rep Date: 2018-01-17 Impact factor: 2.952