C Kabali1, M M Werler. 1. Boston University School of Public Health, Boston, Massachusetts, USA.
Abstract
OBJECTIVE: Pre-pregnancy overweight and excess weight gain during pregnancy have each been associated with an increased risk of delivering large babies. However, previous studies have focused on the separate effects of these two indices of weight in diabetic women. METHOD: This study analyzed both separate and combined effects of pre-pregnant body mass index and weight gain in relation to macrosomia (> or =4000 g) in offspring among 815 non-diabetic women, using data collected from a retrospective study. RESULT: Compared to mothers with normal pre-pregnancy BMI and pregnancy weight gain, risk of macrosomia in offspring was significantly elevated only in overweight women with excess weight gain (adjusted OR=2.6, 95% CI [1.2,5.4]) but not among normal weight mothers with excess gain (adjusted OR=1.1, 95% CI [0.5,2.4]) or overweight mothers with normal or low gain (adjusted OR=1.1, 95% CI [0.4,3.1]). CONCLUSION: Given the complications that are associated with delivering large babies, overweight women may benefit from not gaining excess weight in pregnancy.
OBJECTIVE: Pre-pregnancy overweight and excess weight gain during pregnancy have each been associated with an increased risk of delivering large babies. However, previous studies have focused on the separate effects of these two indices of weight in diabeticwomen. METHOD: This study analyzed both separate and combined effects of pre-pregnant body mass index and weight gain in relation to macrosomia (> or =4000 g) in offspring among 815 non-diabeticwomen, using data collected from a retrospective study. RESULT: Compared to mothers with normal pre-pregnancy BMI and pregnancy weight gain, risk of macrosomia in offspring was significantly elevated only in overweight women with excess weight gain (adjusted OR=2.6, 95% CI [1.2,5.4]) but not among normal weight mothers with excess gain (adjusted OR=1.1, 95% CI [0.5,2.4]) or overweight mothers with normal or low gain (adjusted OR=1.1, 95% CI [0.4,3.1]). CONCLUSION: Given the complications that are associated with delivering large babies, overweight women may benefit from not gaining excess weight in pregnancy.
Authors: Martha M Werler; Jane E Sheehan; Catherine Hayes; Bonnie L Padwa; Allen A Mitchell; John B Mulliken Journal: Cleft Palate Craniofac J Date: 2004-09
Authors: Carol S Weisman; Marianne M Hillemeier; Danielle Symons Downs; Cynthia H Chuang; Anne-Marie Dyer Journal: Womens Health Issues Date: 2010-02-04
Authors: Mei-Wei Chang; Susan Nitzke; Roger Brown; M Jean Brancheau Egan; Christopher M Bendekgey; Diana Buist Journal: Contemp Clin Trials Commun Date: 2016-11-24
Authors: Inmaculada Bautista-Castaño; Patricia Henriquez-Sanchez; Nestor Alemán-Perez; Jose J Garcia-Salvador; Alicia Gonzalez-Quesada; Jose A García-Hernández; Luis Serra-Majem Journal: PLoS One Date: 2013-11-20 Impact factor: 3.240