Literature DB >> 17374486

Na+-glucose cotransporter (SGLT) inhibitory flavonoids from the roots of Sophora flavescens.

Seizo Sato1, Jiro Takeo, Chihiro Aoyama, Hiroyuki Kawahara.   

Abstract

The methanol extract of Sophora flavescens, which is used in traditional Chinese medicine (sophorae radix), showed potent Na(+)-glucose cotransporter (SGLT) inhibitory activity. Our search for active components identified many well-known flavonoid antioxidants: kurarinone, sophoraflavanone G, kushenol K, and kushenol N.

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Year:  2007        PMID: 17374486     DOI: 10.1016/j.bmc.2007.03.011

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  16 in total

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9.  Use of an UHPLC-MS/MS Method for Determination of Kuraridin and Characterization of Its Metabolites in Rat Plasma after Oral Administration.

Authors:  Yi Liu; Lei Chen; Wei Cai; Lin-Lin Zhao; Zhi-Xian Mo
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10.  Asymmetric one-pot transformation of isoflavones to pterocarpans and its application in phytoalexin synthesis.

Authors:  Philipp Ciesielski; Peter Metz
Journal:  Nat Commun       Date:  2020-06-18       Impact factor: 14.919

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