Literature DB >> 17368758

Establishment of a human herpes virus-8-negative malignant effusion lymphoma cell line (STR-428) carrying concurrent translocations of BCL2 and c-MYC genes.

Tamiko Taira1, Akitoshi Nagasaki, Takeaki Tomoyose, Jun-ichi Miyagi, Naoki Kakazu, Shigeyoshi Makino, Tetsuharu Shinjyo, Naoya Taira, Masato Masuda, Nobuyuki Takasu.   

Abstract

A new cell line, STR-428 was established from ascites tumor cells of a malignant effusion lymphoma patient without human herpes virus-8 (HHV-8) infection. STR-428 cells showed an immunophenotype of mature B-cells and produced few cytokines related to lymphomatous effusion. Karyotypic and genetic analysis revealed complex translocations including t(14;18)(q32;q21) effecting IgH/BCL2 and der(8)t(3;8)(q27;q24) involving c-MYC. STR-428 represents a unique, B-cell lymphoma cell line carrying concurrent rearrangement of BCL2 and c-MYC genes with features distinct from those of HHV-8-related primary effusion lymphoma. This cell line may be a valuable tool, other than HHV-8, to investigate the pathogenesis of primary lymphomatous effusion.

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Year:  2007        PMID： 17368758     DOI： 10.1016/j.leukres.2006.12.023

Source DB:  PubMed          Journal:  Leuk Res        ISSN： 0145-2126            Impact factor:   3.156


  6 in total

1.  Molecular cloning of translocation breakpoint from der(8)t(3;8)(q27;q24) defines juxtaposition of downstream of C-MYC and upstream of BCL6.

Authors:  Takashi Sonoki; Hiro Tatetsu; Akitoshi Nagasaki; Hiroyuki Hata
Journal:  Int J Hematol       Date:  2007-08       Impact factor: 2.490

2.  Establishment of CD5 and CD10 double-positive mature B-cell line, WILL1, showing complex 8q24 translocation involving 14q32 and 6q27.

Authors:  Shima Uneda; Minako Gotoh; Takashi Sonoki; Kazuhiro Nishida; Yasushi Nakamura; Miwa Kurimoto; Nobuyoshi Hanaoka; Hiroshi Matsuoka; Masafumi Taniwaki; Hideki Nakakuma
Journal:  Int J Hematol       Date:  2008-10-30       Impact factor: 2.490

Review 3.  Understanding pathogenetic aspects and clinical presentation of primary effusion lymphoma through its derived cell lines.

Authors:  Antonino Carbone; Ethel Cesarman; Annunziata Gloghini; Hans G Drexler
Journal:  AIDS       Date:  2010-02-20       Impact factor: 4.177

Review 4.  Human herpesvirus 8-negative effusion-based large B-cell lymphoma: a distinct entity with unique clinicopathologic characteristics.

Authors:  Savanah D Gisriel; Ji Yuan; Ryan C Braunberger; Danielle L V Maracaja; Xueyan Chen; Xiaojun Wu; Jenna McCracken; Mingyi Chen; Yi Xie; Laura E Brown; Peng Li; Yi Zhou; Tarsheen Sethi; Austin McHenry; Ronald G Hauser; Nathan Paulson; Haiming Tang; Eric D Hsi; Endi Wang; Qian-Yun Zhang; Ken H Young; Mina L Xu; Zenggang Pan
Journal:  Mod Pathol       Date:  2022-05-13       Impact factor: 8.209

5.  Establishment and characterization of a novel 'double-hit' follicular lymphoma cell line, FL-SJC.

Authors:  Min Chen; Guoxiong Jiang; Yichen Liu; Dongya Li; Tiantian Li; Jie Peng; Qian Jiang; Haiyan You; Rong Ba; Jinlan Pan; Mei Li; Weiguo Long; Jinsong Yan; Yan Zhu; Yun Wang; Xiaodong Xi; Jianhua Mao; Xiaofeng Shi
Journal:  J Cell Mol Med       Date:  2020-05-27       Impact factor: 5.310

6.  Development of a novel cell line-derived xenograft model of primary herpesvirus 8-unrelated effusion large B-cell lymphoma and antitumor activity of birabresib in vitro and in vivo.

Authors:  Tomohiro Nishimori; Tomonori Higuchi; Yumiko Hashida; Takako Ujihara; Ayuko Taniguchi; Fumiya Ogasawara; Naoya Kitamura; Ichiro Murakami; Kensuke Kojima; Masanori Daibata
Journal:  Cancer Med       Date:  2021-11-24       Impact factor: 4.452
  6 in total

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