| Literature DB >> 17368001 |
H Randall Griffith1, Roy C Martin, Jennifer K Bambara, Edward Faught, Laura K Vogtle, Daniel C Marson.
Abstract
Little is known about cognitive functioning of older adults with chronic partial epilepsy. We examined cognitive performance of this epilepsy patient group over 2-3 years. Seventeen older adults with epilepsy and 17 healthy older adults were administered measures of overall cognition and verbal memory at baseline and 2-3 years later. At baseline, older adults with epilepsy performed below controls on overall cognition and verbal memory (p's<0.001). These deficits generally remained stable at follow-up, although executive control appeared to decline (p<0.05). Older adults with epilepsy showed a failure to benefit from practice on a verbal memory measure (p=0.017). Older adults with epilepsy demonstrated cognitive deficits that generally are not progressive. A failure to benefit from repeat exposure to a Delayed Recall task could indicate learning deficits. These patients may also progressively lose executive control, possibly as a result of accelerated aging.Entities:
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Year: 2007 PMID： 17368001 DOI： 10.1016/j.eplepsyres.2007.01.002
Source DB: PubMed Journal: Epilepsy Res ISSN： 0920-1211 Impact factor: 3.045