Literature DB >> 1736768

Treating sickle cell pain like cancer pain.

D Brookoff1, R Polomano.   

Abstract

OBJECTIVE: To assess the effect of a structured analgesic regimen on hospital use by patients with sickle cell disease. INTERVENTION: Intravenous and oral controlled-release morphine was used instead of intramuscular meperidine and short-acting oral opioids for the treatment of sickle cell pain.
DESIGN: Time series in which emergency and admission records for four 6-month periods before and two 6-month periods after the institution of the new analgesic protocol were reviewed.
SETTING: Inner-city university hospital providing care for adults with sickle cell disease. PATIENTS: All patients (an average of 50) who used the emergency department of the inpatient medical service for treatment of sickle cell crisis during the study periods.
MEASUREMENTS AND MAIN RESULTS: The number of admissions for sickle cell pain decreased by 44%, total inpatient days by 57%, length of hospital stay by 23%, and the number of emergency department visits by 67% after initiation of the morphine protocol. Hospital use remained at these lower levels one year later. Similar declines were seen for a subset of 15 patients who had a history of frequent admissions for sickle cell pain and who used this hospital exclusively and accounted for more than half of the admissions for sickle cell disease.
CONCLUSIONS: A pain-control program modeled on regimens used to treat chronic cancer pain reduced hospital use by adult patients with sickle cell pain.

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Year:  1992        PMID: 1736768     DOI: 10.7326/0003-4819-116-5-364

Source DB:  PubMed          Journal:  Ann Intern Med        ISSN: 0003-4819            Impact factor:   25.391


  16 in total

Review 1.  Opioids in chronic pain management: is there a significant risk of addiction?

Authors:  G M Aronoff
Journal:  Curr Rev Pain       Date:  2000

Review 2.  Management of pain in sickle-cell disease.

Authors:  Iheanyi Okpala; Adel Tawil
Journal:  J R Soc Med       Date:  2002-09       Impact factor: 5.344

3.  Abuse potential of various opioid medications.

Authors:  D Brookoff
Journal:  J Gen Intern Med       Date:  1993-12       Impact factor: 5.128

4.  Randomized clinical trial of computerized PAINRelieveIt® for patients with sickle cell disease: PAINReportIt® and PAINUCope®.

Authors:  Brenda W Dyal; Miriam O Ezenwa; Yingwei Yao; Robert E Molokie; Zaijie J Wang; Samir K Ballas; Marie L Suarez; Diana J Wilkie
Journal:  Patient Educ Couns       Date:  2019-08-17

5.  Differences in Sensory Pain, Expectation, and Satisfaction Reported by Outpatients with Cancer or Sickle Cell Disease.

Authors:  Miriam O Ezenwa; Robert E Molokie; Zaijie Jim Wang; Yingwei Yao; Marie L Suarez; Brenda Dyal; Khulud Abudawood; Diana J Wilkie
Journal:  Pain Manag Nurs       Date:  2018-03-01       Impact factor: 1.929

6.  Respect, trust, and the management of sickle cell disease pain in hospital: comparative analysis of concern-raising behaviors, preliminary model, and agenda for international collaborative research to inform practice.

Authors:  James Elander; Mary Catherine Beach; Carlton Haywood
Journal:  Ethn Health       Date:  2011 Aug-Oct       Impact factor: 2.772

Review 7.  Opioid analgesics: comparative features and prescribing guidelines.

Authors:  N I Cherny
Journal:  Drugs       Date:  1996-05       Impact factor: 9.546

8.  Outpatient management of sickle cell pain with chronic opioid pharmacotherapy.

Authors:  Lauren Shaiova; David Wallenstein
Journal:  J Natl Med Assoc       Date:  2004-07       Impact factor: 1.798

Review 9.  State of the Art Management of Acute Vaso-occlusive Pain in Sickle Cell Disease.

Authors:  Latika Puri; Kerri A Nottage; Jane S Hankins; Doralina L Anghelescu
Journal:  Paediatr Drugs       Date:  2018-02       Impact factor: 3.022

Review 10.  Sickle Cell Disease and the Respiratory System: A Tangential Perspective to the Hematopulmonological Dilemma.

Authors:  Ibrahim Sange; Phani Bhavana Cherukuri; Vaishnavi Parchuri; Natasha Srinivas; Sruthi Priyavadhana Ramanan; Aliya H Sange; Srimy Modi; Farhat A Khot
Journal:  Cureus       Date:  2021-06-10
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