Literature DB >> 17366287

Management of hepatitis C among drug users attending general practice in Ireland: baseline data from the Dublin area hepatitis C in general practice initiative.

Walter Cullen1, June Stanley, Deirdre Langton, Yvonne Kelly, Gerard Bury.   

Abstract

OBJECTIVE: In Ireland, general practice is increasingly providing long-term care for injecting drug users, 62-81% of whom are infected with hepatitis C (HCV). Clinical guidelines for the management of HCV among drug users have recently been developed in Ireland, and this study aimed to describe HCV care among drug users attending general practice in the greater Dublin area, prior to the implementation of the clinical practice guidelines.
METHODS: The clinical records of 196 patients attending 25 general practices in the Eastern Regional Health Authority area of Ireland for methadone maintenance treatment were examined on site and anonymized data collected on HCV care processes.
RESULTS: Patients had been attending general practice for methadone maintenance treatment for a mean of 30.7 months, 72% were male and 51% had provided a urine sample testing positive for metabolites of drugs of abuse other than methadone in the previous 3 months. There was evidence that 77%, 69% and 60% had been screened for HCV, human immunodeficiency virus (HIV) and hepatitis B (HBV), respectively. Among those who had been tested, the prevalence of HCV, HIV and HBV infection was 69%, 10% and 11%, respectively. Of those known to be HCV positive, 36 (35%) had been tested for HCV-RNA (29 testing positive), 31 (30%) had been referred to a hepatology clinic, 24 (23%) had attended a clinic, 13 (13%) had a liver biopsy performed and three (3%) had started treatment for HCV.
CONCLUSION: While the majority of patients have been screened for blood-borne viruses, a minority of those infected with HCV have had subsequent investigations or treatment. New interventions to facilitate optimum care in this regard need to be considered.

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Year:  2007        PMID: 17366287     DOI: 10.1080/14017430601049365

Source DB:  PubMed          Journal:  Eur J Gen Pract        ISSN: 1381-4788            Impact factor:   1.904


  11 in total

1.  The natural history of injecting drug use: a 25-year longitudinal study of a cohort of injecting drug users in inner city Dublin.

Authors:  F D O'Kelly; C M O'Kelly
Journal:  Ir J Med Sci       Date:  2012-03-20       Impact factor: 1.568

2.  Healthcare contact and treatment uptake following hepatitis C virus screening and counseling among rural Appalachian people who use drugs.

Authors:  Dustin B Stephens; April M Young; Jennifer R Havens
Journal:  Int J Drug Policy       Date:  2017-06-23

Review 3.  HepCare Ireland-a service innovation project.

Authors:  Stephen P Connolly; Gordana Avramovic; Walter Cullen; Tina McHugh; Eileen O'Connor; Geoff Mc Combe; Des Crowley; Anna Marie Naughton; Aidan Horan; John S Lambert
Journal:  Ir J Med Sci       Date:  2020-08-06       Impact factor: 1.568

Review 4.  A systematic review of Hepatitis C virus treatment uptake among people who inject drugs in the European Region.

Authors:  Jeffrey V Lazarus; Ida Sperle; Mojca Maticic; Lucas Wiessing
Journal:  BMC Infect Dis       Date:  2014-09-19       Impact factor: 3.090

Review 5.  Hepatitis C virus infection epidemiology among people who inject drugs in Europe: a systematic review of data for scaling up treatment and prevention.

Authors:  Lucas Wiessing; Marica Ferri; Bart Grady; Maria Kantzanou; Ida Sperle; Katelyn J Cullen; Angelos Hatzakis; Maria Prins; Peter Vickerman; Jeffrey V Lazarus; Vivian D Hope; Catharina Matheï
Journal:  PLoS One       Date:  2014-07-28       Impact factor: 3.240

Review 6.  Hepatitis C virus infection in Irish drug users and prisoners - a scoping review.

Authors:  D Crowley; R Murtagh; W Cullen; J S Lambert; T McHugh; M C Van Hout
Journal:  BMC Infect Dis       Date:  2019-08-08       Impact factor: 3.090

7.  Integrating Hepatitis C Care for Opioid Substitution Treatment Patients Attending General Practice: Feasibility, Clinical, and Cost-Effectiveness Analysis.

Authors:  Geoff McCombe; Davina Swan; John S Lambert; Eileen O'Connor; Zoe Ward; Peter Vickerman; Gordana Avramovic; Des Crowley; Willard Tinago; Nyashadzaishe Mafirakureva; Walter Cullen
Journal:  Interact J Med Res       Date:  2022-08-23

8.  Chronic illness and multimorbidity among problem drug users: a comparative cross sectional pilot study in primary care.

Authors:  Walter Cullen; Sarah O'Brien; Austin O'Carroll; Fergus D O'Kelly; Gerard Bury
Journal:  BMC Fam Pract       Date:  2009-04-21       Impact factor: 2.497

9.  Integrated Hepatitis C Care for People Who Inject Drugs (Heplink): Protocol for a Feasibility Study in Primary Care.

Authors:  Geoff McCombe; Davina Swan; Eileen O'Connor; Gordana Avramovic; Peter Vickerman; Zoe Ward; Julian Surey; Juan Macías; John S Lambert; Walter Cullen
Journal:  JMIR Res Protoc       Date:  2018-06-04

10.  Incidence of hepatitis C among people who inject drugs in Ireland.

Authors:  Anne Marie Carew; Niamh Murphy; Jean Long; Kate Hunter; Suzi Lyons; Cathal Walsh; Lelia Thornton
Journal:  Hepatol Med Policy       Date:  2017-01-26
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