AIM: To use the superior spatial resolution of magnetic resonance imaging (MRI) to examine differences in cerebral perfusion between young alcohol dependent and normal women. METHODS: Eight alcohol dependent women and 8 controls (all ages 18-25) received single-slice resting perfusion-weighted MRI (directly proportional to brain blood flow), with slices located above the corpus callosum. RESULTS: Alcohol-dependent women had decreased perfusion in prefrontal and left parietal regions. CONCLUSIONS: Reduced perfusion has not previously been reported in young, physically healthy alcohol dependent females, yet is consistent with previously reported decreased cerebral activity in alcohol dependence.
AIM: To use the superior spatial resolution of magnetic resonance imaging (MRI) to examine differences in cerebral perfusion between young alcohol dependent and normal women. METHODS: Eight alcohol dependent women and 8 controls (all ages 18-25) received single-slice resting perfusion-weighted MRI (directly proportional to brain blood flow), with slices located above the corpus callosum. RESULTS:Alcohol-dependent women had decreased perfusion in prefrontal and left parietal regions. CONCLUSIONS: Reduced perfusion has not previously been reported in young, physically healthy alcohol dependent females, yet is consistent with previously reported decreased cerebral activity in alcohol dependence.
Authors: J L Lancaster; M G Woldorff; L M Parsons; M Liotti; C S Freitas; L Rainey; P V Kochunov; D Nickerson; S A Mikiten; P T Fox Journal: Hum Brain Mapp Date: 2000-07 Impact factor: 5.038
Authors: Camellia P Clark; Gregory G Brown; Sarah L Archibald; Christine Fennema-Notestine; Deborah R Braun; Linda S Thomas; Ashley N Sutherland; J Christian Gillin Journal: Psychiatry Res Date: 2005-12-27 Impact factor: 3.222
Authors: G J Wang; N D Volkow; D Franceschi; J S Fowler; P K Thanos; N Scherbaum; N Pappas; C T Wong; R J Hitzemann; C A Felder Journal: Alcohol Clin Exp Res Date: 2000-06 Impact factor: 3.455
Authors: Camellia P Clark; Gregory G Brown; Lawrence Frank; Linda Thomas; Ashley N Sutherland; J Christian Gillin Journal: Psychiatry Res Date: 2006-03-20 Impact factor: 3.222
Authors: Bennett A Landman; Alan J Huang; Aliya Gifford; Deepti S Vikram; Issel Anne L Lim; Jonathan A D Farrell; John A Bogovic; Jun Hua; Min Chen; Samson Jarso; Seth A Smith; Suresh Joel; Susumu Mori; James J Pekar; Peter B Barker; Jerry L Prince; Peter C M van Zijl Journal: Neuroimage Date: 2010-11-20 Impact factor: 6.556
Authors: Adolf Pfefferbaum; Sandra Chanraud; Anne-Lise Pitel; Ajit Shankaranarayanan; David C Alsop; Torsten Rohlfing; Edith V Sullivan Journal: Psychiatry Res Date: 2010-05-20 Impact factor: 3.222
Authors: Donna E Murray; Timothy C Durazzo; Thomas P Schmidt; Troy A Murray; Christoph Abé; Joseph Guydish; Dieter J Meyerhoff Journal: Addict Biol Date: 2017-06-19 Impact factor: 4.280
Authors: Amy E Ramage; Ai-Ling Lin; Rene L Olvera; Peter T Fox; Douglas E Williamson Journal: Drug Alcohol Depend Date: 2015-01-20 Impact factor: 4.492
Authors: Claire E Wilcox; Charlene J Dekonenko; Andrew R Mayer; Michael P Bogenschutz; Jessica A Turner Journal: Rev Neurosci Date: 2014 Impact factor: 4.353