Literature DB >> 17365687

Tambouranolide, a new cytotoxic hydroxybutanolide from a Tambourissa sp. (Monimiaceae).

Brent J Yoder1, Shugeng Cao, Andrew Norris, James S Miller, Fidisoa Ratovoson, Rabodo Andriantsiferana, Vincent E Rasamison, David G I Kingston.   

Abstract

A new cytotoxic hydroxybutanolide, tambouranolide, has been isolated by solid phase extraction from an ethanol extract of the dried roots of a species of Tambourissa (Monimiaceae) from the Madagascar rainforest. The structure was elucidated through the interpretation of spectral data and its comparison to data reported in the literature for related molecules. The compound showed moderate in vitro cytotoxicity with an IC50 of 8 micro g mL(-1) in the A2780 human ovarian cancer cell line assay.

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Year:  2007        PMID: 17365687      PMCID: PMC2782940          DOI: 10.1080/14786410500445574

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN: 1478-6419            Impact factor:   2.861


  6 in total

1.  Cytotoxic flavanones of Schizolaena hystrix from the Madagascar rainforest.

Authors:  Brian T Murphy; Shugeng Cao; Andrew Norris; James S Miller; Fidisoa Ratovoson; Rabodo Andriantsiferana; Vincent E Rasamison; David G I Kingston
Journal:  J Nat Prod       Date:  2005-03       Impact factor: 4.050

2.  Identification of volatile constituents of Tambourissa leptophylla.

Authors:  S Gallori; A R Bilia; N Mulinacci; C Bicchi; P Rubiolo; F F Vincieri
Journal:  Planta Med       Date:  2001-04       Impact factor: 3.352

3.  Biologically active gamma-lactones and methylketoalkenes from Lindera benzoin.

Authors:  J E Anderson; W W Ma; D L Smith; C J Chang; J L McLaughlin
Journal:  J Nat Prod       Date:  1992-01       Impact factor: 4.050

4.  Cytotoxic and other compounds from Didymochlaena truncatula from the Madagascar rain forest.

Authors:  Shugeng Cao; Mohamed M Radwan; Andrew Norris; James S Miller; Fidy Ratovoson; Andrianjafy Mamisoa; Rabodo Andriantsiferana; Vincent E Rasamison; Stephan Rakotonandrasana; David G I Kingston
Journal:  J Nat Prod       Date:  2006-02       Impact factor: 4.050

5.  Cytotoxic diterpenes from Cassipourea madagascariensis from the Madagascar rainforest.

Authors:  V S Prakash Chaturvedula; Andrew Norris; James S Miller; Fidisoa Ratovoson; Rabodo Andriantsiferana; Vincent E Rasamison; David G I Kingston
Journal:  J Nat Prod       Date:  2006-02       Impact factor: 4.050

6.  Radiation survival parameters of antineoplastic drug-sensitive and -resistant human ovarian cancer cell lines and their modification by buthionine sulfoximine.

Authors:  K G Louie; B C Behrens; T J Kinsella; T C Hamilton; K R Grotzinger; W M McKoy; M A Winker; R F Ozols
Journal:  Cancer Res       Date:  1985-05       Impact factor: 12.701

  6 in total
  2 in total

1.  Isolation, Structure Elucidation, and Antiproliferative Activity of Butanolides and Lignan Glycosides from the Fruit of Hernandia nymphaeifolia.

Authors:  Simayijiang Aimaiti; Yohei Saito; Shuichi Fukuyoshi; Masuo Goto; Katsunori Miyake; David J Newman; Barry R O'Keefe; Kuo-Hsiung Lee; Kyoko Nakagawa-Goto
Journal:  Molecules       Date:  2019-11-05       Impact factor: 4.411

2.  LAMA-1: A Cerebroside Isolated from the Deep-Sea-Derived Fungus Penicillium chrysogenum.

Authors:  Samah O Alshehri; Rania T Malatani; Hanin A Bogari; Ahmad O Noor; Amany K Ibrahim; Sameh S Elhady; Reda F A Abdelhameed
Journal:  Metabolites       Date:  2020-02-20
  2 in total

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