| Literature DB >> 17365687 |
Brent J Yoder1, Shugeng Cao, Andrew Norris, James S Miller, Fidisoa Ratovoson, Rabodo Andriantsiferana, Vincent E Rasamison, David G I Kingston.
Abstract
A new cytotoxic hydroxybutanolide, tambouranolide, has been isolated by solid phase extraction from an ethanol extract of the dried roots of a species of Tambourissa (Monimiaceae) from the Madagascar rainforest. The structure was elucidated through the interpretation of spectral data and its comparison to data reported in the literature for related molecules. The compound showed moderate in vitro cytotoxicity with an IC50 of 8 micro g mL(-1) in the A2780 human ovarian cancer cell line assay.Entities:
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Year: 2007 PMID: 17365687 PMCID: PMC2782940 DOI: 10.1080/14786410500445574
Source DB: PubMed Journal: Nat Prod Res ISSN: 1478-6419 Impact factor: 2.861