Literature DB >> 17365173

The Sep15 protein family: roles in disulfide bond formation and quality control in the endoplasmic reticulum.

Vyacheslav M Labunskyy1, Dolph L Hatfield, Vadim N Gladyshev.   

Abstract

Disulfide bonds play an important role in the structure and function of membrane and secretory proteins. The formation of disulfide bonds in the endoplasmic reticulum (ER) of eukaryotic cells is catalyzed by a complex network of thiol-disulfide oxidoreductases. Whereas a number of ER-resident oxidoreductases have been identified, the function of only a few of them is firmly established. Recently, a selenocysteine-containing oxidoreductase, Sep15, has been implicated in disulfide bond assisted protein folding, and a role in quality control for this selenoprotein has been proposed. This review summarizes up-to-date information on the Sep15 family proteins and highlights new insights into their physiological function.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17365173     DOI： 10.1080/15216540601126694

Source DB:  PubMed          Journal:  IUBMB Life        ISSN： 1521-6543            Impact factor:   3.885


  49 in total

Review 1.  Getting in and out from calnexin/calreticulin cycles.

Authors:  Julio J Caramelo; Armando J Parodi
Journal:  J Biol Chem       Date:  2008-02-26       Impact factor: 5.157

Review 2.  Selenoproteins in colon cancer.

Authors:  Kristin M Peters; Bradley A Carlson; Vadim N Gladyshev; Petra A Tsuji
Journal:  Free Radic Biol Med       Date:  2018-05-22       Impact factor: 7.376

Review 3.  Selenoproteins: molecular pathways and physiological roles.

Authors:  Vyacheslav M Labunskyy; Dolph L Hatfield; Vadim N Gladyshev
Journal:  Physiol Rev       Date:  2014-07       Impact factor: 37.312

Review 4.  Understanding selenoprotein function and regulation through the use of rodent models.

Authors:  Marina V Kasaikina; Dolph L Hatfield; Vadim N Gladyshev
Journal:  Biochim Biophys Acta       Date:  2012-03-13

5.  Transcriptome profile analysis reveals specific signatures of pollutants in Atlantic eels.

Authors:  Lucie Baillon; Fabien Pierron; Raphaël Coudret; Eric Normendeau; Antoine Caron; Laurent Peluhet; Pierre Labadie; Hélène Budzinski; Gilles Durrieu; Jérôme Sarraco; Pierre Elie; Patrice Couture; Magalie Baudrimont; Louis Bernatchez
Journal:  Ecotoxicology       Date:  2014-09-26       Impact factor: 2.823

6.  Deficiency in the 15-kDa selenoprotein inhibits tumorigenicity and metastasis of colon cancer cells.

Authors:  Robert Irons; Petra A Tsuji; Bradley A Carlson; Ping Ouyang; Min-Hyuk Yoo; Xue-Ming Xu; Dolph L Hatfield; Vadim N Gladyshev; Cindy D Davis
Journal:  Cancer Prev Res (Phila)       Date:  2010-04-13

7.  Roles of the 15-kDa selenoprotein (Sep15) in redox homeostasis and cataract development revealed by the analysis of Sep 15 knockout mice.

Authors:  Marina V Kasaikina; Dmitri E Fomenko; Vyacheslav M Labunskyy; Salil A Lachke; Wenya Qiu; Juliet A Moncaster; Jie Zhang; Mark W Wojnarowicz; Sathish Kumar Natarajan; Mikalai Malinouski; Ulrich Schweizer; Petra A Tsuji; Bradley A Carlson; Richard L Maas; Marjorie F Lou; Lee E Goldstein; Dolph L Hatfield; Vadim N Gladyshev
Journal:  J Biol Chem       Date:  2011-07-18       Impact factor: 5.157

8.  A large prospective study of SEP15 genetic variation, interaction with plasma selenium levels, and prostate cancer risk and survival.

Authors:  Kathryn L Penney; Fredrick R Schumacher; Haojie Li; Peter Kraft; J Steven Morris; Tobias Kurth; Lorelei A Mucci; David J Hunter; Philip W Kantoff; Meir J Stampfer; Jing Ma
Journal:  Cancer Prev Res (Phila)       Date:  2010-04-27

Review 9.  Molecular mechanisms by which selenoproteins affect cancer risk and progression.

Authors:  Pin Zhuo; Alan M Diamond
Journal:  Biochim Biophys Acta       Date:  2009-03-13

Review 10.  The human selenoproteome: recent insights into functions and regulation.

Authors:  M A Reeves; P R Hoffmann
Journal:  Cell Mol Life Sci       Date:  2009-04-28       Impact factor: 9.261
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.