Literature DB >> 17363954

Tightening the epidermal barrier with atypical PKCs.

Mitchell F Denning1.   

Abstract

The permeability barrier function of the epidermis is one of the most vital jobs performed by the skin; however, our understanding of the function and regulation of tight junctions in the epidermis remains limited. Helfrich et al. identify a key role for atypical protein kinase C (aPKC) activity, as a component of the Par3-Par6 polarity complex, in epidermal barrier function.

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Year:  2007        PMID： 17363954     DOI： 10.1038/sj.jid.5700694

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


  2 in total

1.  Blood vessel epicardial substance (Bves) regulates epidermal tight junction integrity through atypical protein kinase C.

Authors:  Yu-Ching Wu; Chia-Yang Liu; Yau-Hung Chen; Ruei-Feng Chen; Chang-Jen Huang; I-Jong Wang
Journal:  J Biol Chem       Date:  2012-09-27       Impact factor: 5.157

2.  Deregulation of keratinocyte differentiation and activation: a hallmark of venous ulcers.

Authors:  Olivera Stojadinovic; Irena Pastar; Sasa Vukelic; My G Mahoney; Donna Brennan; Agata Krzyzanowska; Michael Golinko; Harold Brem; Marjana Tomic-Canic
Journal:  J Cell Mol Med       Date:  2008-03-28       Impact factor: 5.310
  2 in total

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