Literature DB >> 17363512

Targeting the molecular chaperone heat shock protein 90 provides a multifaceted effect on diverse cell signaling pathways of cancer cells.

Wanping Xu1, Len Neckers.   

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Year:  2007        PMID： 17363512     DOI： 10.1158/1078-0432.CCR-06-2966

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN： 1078-0432            Impact factor:   12.531


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  78 in total

1.  Antitumor activity of efrapeptins, alone or in combination with 2-deoxyglucose, in breast cancer in vitro and in vivo.

Authors:  Adonia E Papathanassiu; Nicholas J MacDonald; David R Emlet; Hong A Vu
Journal:  Cell Stress Chaperones       Date:  2010-10-07       Impact factor: 3.667

Review 2.  Anticancer Inhibitors of Hsp90 Function: Beyond the Usual Suspects.

Authors:  Gaurav Garg; Anuj Khandelwal; Brian S J Blagg
Journal:  Adv Cancer Res       Date:  2016-02-10       Impact factor: 6.242

3.  The multiple roles of computational chemistry in fragment-based drug design.

Authors:  Richard Law; Oliver Barker; John J Barker; Thomas Hesterkamp; Robert Godemann; Ole Andersen; Tara Fryatt; Steve Courtney; Dave Hallett; Mark Whittaker
Journal:  J Comput Aided Mol Des       Date:  2009-06-17       Impact factor: 3.686

4.  Evaluating melanoma drug response and therapeutic escape with quantitative proteomics.

Authors:  Vito W Rebecca; Elizabeth Wood; Inna V Fedorenko; Kim H T Paraiso; H Eirik Haarberg; Yi Chen; Yun Xiang; Amod Sarnaik; Geoffrey T Gibney; Vernon K Sondak; John M Koomen; Keiran S M Smalley
Journal:  Mol Cell Proteomics       Date:  2014-04-23       Impact factor: 5.911

5.  Compound ranking based on a new mathematical measure of effectiveness using time course data from cell-based assays.

Authors:  Francisco J Diaz; Peter R McDonald; Anuradha Roy; Byron Taylor; Ashleigh Price; Jessica Hall; Brian S J Blagg; Rathnam Chaguturu
Journal:  Comb Chem High Throughput Screen       Date:  2013-03       Impact factor: 1.339

6.  Ganetespib (STA-9090), a nongeldanamycin HSP90 inhibitor, has potent antitumor activity in in vitro and in vivo models of non-small cell lung cancer.

Authors:  Takeshi Shimamura; Samanthi A Perera; Kevin P Foley; Jim Sang; Scott J Rodig; Takayo Inoue; Liang Chen; Danan Li; Julian Carretero; Yu-Chen Li; Papiya Sinha; Christopher D Carey; Christa L Borgman; John-Paul Jimenez; Matthew Meyerson; Weiwen Ying; James Barsoum; Kwok-Kin Wong; Geoffrey I Shapiro
Journal:  Clin Cancer Res       Date:  2012-07-17       Impact factor: 12.531

Review 7.  Connection between inflammation and carcinogenesis in gastrointestinal tract: focus on TGF-beta signaling.

Authors:  Suntaek Hong; Ho-Jae Lee; Seong Jin Kim; Ki-Baik Hahm
Journal:  World J Gastroenterol       Date:  2010-05-07       Impact factor: 5.742

8.  Hydrogen sulfide attenuates hepatic ischemia-reperfusion injury: role of antioxidant and antiapoptotic signaling.

Authors:  Saurabh Jha; John W Calvert; Mark R Duranski; Arun Ramachandran; David J Lefer
Journal:  Am J Physiol Heart Circ Physiol       Date:  2008-06-20       Impact factor: 4.733

9.  Targeted inhibition of the molecular chaperone Hsp90 overcomes ALK inhibitor resistance in non-small cell lung cancer.

Authors:  Jim Sang; Jaime Acquaviva; Julie C Friedland; Donald L Smith; Manuel Sequeira; Chaohua Zhang; Qin Jiang; Liquan Xue; Christine M Lovly; John-Paul Jimenez; Alice T Shaw; Robert C Doebele; Suqin He; Richard C Bates; D Ross Camidge; Stephan W Morris; Iman El-Hariry; David A Proia
Journal:  Cancer Discov       Date:  2013-03-26       Impact factor: 39.397

10.  Synthesis and biological evaluation of coumarin replacements of novobiocin as Hsp90 inhibitors.

Authors:  Bhaskar Reddy Kusuma; Anuj Khandelwal; Wen Gu; Douglas Brown; Weiya Liu; George Vielhauer; Jeffrey Holzbeierlein; Brian S J Blagg
Journal:  Bioorg Med Chem       Date:  2014-01-03       Impact factor: 3.641
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