| Literature DB >> 17363116 |
Houxing Fan1, Gang Xu, Yilang Chen, Zhiteng Jiang, Shuhua Zhang, Yushe Yang, Ruyun Ji.
Abstract
A new series of oxazolidinones containing triazolyl group has been synthesized and tested for in vitro antibacterial activity by MIC determination against a panel of resistant and susceptible Gram-positive organisms. Most of the analogs in this series displayed activity superior to linezolid and vancomycin in vitro. Further, in vivo efficacies of the selected oxazolidinones were also disclosed herein.Entities:
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Year: 2007 PMID： 17363116 DOI： 10.1016/j.ejmech.2007.01.012
Source DB: PubMed Journal: Eur J Med Chem ISSN： 0223-5234 Impact factor: 6.514