Literature DB >> 17361837

[Miltefosine for disseminated cutaneous leishmaniasis].

Lina María González1, Iván Darío Vélez.   

Abstract

Disseminated cutaneous leishmaniasis is a rare presentation characterized by hematogenous dissemination of the parasite that causes the appearance of multiple nodules and plaques in the skin of the whole body and even including the nasal mucous membrane. It differs from diffuse cutaneous leishmaniasis because the alteration in cellular immunity is lower and the lesions may have epidermal desquamation. On the other hand, diffuse cutaneous leishmaniasis presents nodular lesions and a specific anergy in the immune response directed against the parasite. This article describes the case of a Colombian patient with disseminated cutaneous leishmaniasis caused by L. (V) panamensis. The initial treatments with Glucantime and Amphotericin B failed, but his lesions healed after treatment with miltefosine.

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Year:  2006        PMID: 17361837

Source DB:  PubMed          Journal:  Biomedica        ISSN: 0120-4157            Impact factor:   0.935


  3 in total

1.  Efficacy of miltefosine for the treatment of American cutaneous leishmaniasis.

Authors:  Iván Vélez; Liliana López; Ximena Sánchez; Laureano Mestra; Carlos Rojas; Erwin Rodríguez
Journal:  Am J Trop Med Hyg       Date:  2010-08       Impact factor: 2.345

2.  Disseminated leishmaniasis: clinical, pathogenic, and therapeutic aspects.

Authors:  Gustavo Uzêda Machado; Fernanda Ventin Prates; Paulo Roberto Lima Machado
Journal:  An Bras Dermatol       Date:  2019 Jan-Feb       Impact factor: 1.896

3.  Disseminated Cutaneous Leishmaniasis in Colombia: Report of 27 Cases.

Authors:  Iván D Vélez; Alejandra Jiménez; Daniel Vásquez; Sara M Robledo
Journal:  Case Rep Dermatol       Date:  2015-10-07
  3 in total

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