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Literature DB >> 17360323

New tools to build synthetic hormonal pathways.

Bruce R Conklin¹.

Abstract

Mesh：

Substances：

Year: 2007 PMID： 17360323 PMCID： PMC1829213 DOI： 10.1073/pnas.0700913104

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

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15 in total

Review 1. Inherited diseases involving g proteins and g protein-coupled receptors.

Authors: Allen M Spiegel; Lee S Weinstein
Journal: Annu Rev Med Date: 2004 Impact factor: 13.739

2. Unravelling multiple ligand-activation binding sites using RASSL receptors.

Authors: Petrus J Pauwels
Journal: Trends Pharmacol Sci Date: 2003-10 Impact factor: 14.819

3. A G(q/11)-coupled mutant histamine H(1) receptor F435A activated solely by synthetic ligands (RASSL).

Authors: Martijn Bruysters; Aldo Jongejan; Atilla Akdemir; Remko A Bakker; Rob Leurs
Journal: J Biol Chem Date: 2005-07-18 Impact factor: 5.157

4. Allele-specific activation of genetically engineered receptors.

Authors: C D Strader; T Gaffney; E E Sugg; M R Candelore; R Keys; A A Patchett; R A Dixon
Journal: J Biol Chem Date: 1991-01-05 Impact factor: 5.157

5. Controlling signaling with a specifically designed Gi-coupled receptor.

Authors: P Coward; H G Wada; M S Falk; S D Chan; F Meng; H Akil; B R Conklin
Journal: Proc Natl Acad Sci U S A Date: 1998-01-06 Impact factor: 11.205

6. Receptor for motilin identified in the human gastrointestinal system.

Authors: S D Feighner; C P Tan; K K McKee; O C Palyha; D L Hreniuk; S S Pong; C P Austin; D Figueroa; D MacNeil; M A Cascieri; R Nargund; R Bakshi; M Abramovitz; R Stocco; S Kargman; G O'Neill; L H Van Der Ploeg; J Evans; A A Patchett; R G Smith; A D Howard
Journal: Science Date: 1999-06-25 Impact factor: 47.728

New tools to build synthetic hormonal pathways.

Review 1. Inherited diseases involving g proteins and g protein-coupled receptors.

2. Unravelling multiple ligand-activation binding sites using RASSL receptors.

3. A G(q/11)-coupled mutant histamine H(1) receptor F435A activated solely by synthetic ligands (RASSL).

4. Allele-specific activation of genetically engineered receptors.

5. Controlling signaling with a specifically designed Gi-coupled receptor.

6. Receptor for motilin identified in the human gastrointestinal system.

7. Conditional expression and signaling of a specifically designed Gi-coupled receptor in transgenic mice.

8. The receptors and coding logic for bitter taste.

Review 9. Engineering the melanocortin-4 receptor to control G(s) signaling in vivo.

10. Transcriptional activation by tetracyclines in mammalian cells.

1. Engineering a GPCR-ligand pair that simulates the activation of D(2L) by Dopamine.

2. Marking embryonic stem cells with a 2A self-cleaving peptide: a NKX2-5 emerald GFP BAC reporter.