Literature DB >> 17359609

Clinical symptoms and 'off-label' prescribing in children with asthma.

Colin McCowan1, Gaylor Hoskins, Ron G Neville.   

Abstract

A UK-wide database of structured asthma review consultations was used to investigate the prevalence of 'off-label' anti-asthma prescriptions in relationship to clinical symptoms of asthma control. The 1050 children (6.1%) aged 16 years or under issued with an off-label prescription reported more nighttime, daytime and activity asthma symptoms, and used more short-acting beta(2)-agonist medication than their peers. Off-label prescribing for children with asthma in UK primary care is associated with worse levels of self-reported asthma control.

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Year:  2007        PMID： 17359609      PMCID： PMC2042555     

Source DB:  PubMed          Journal:  Br J Gen Pract        ISSN： 0960-1643            Impact factor:   5.386


  9 in total

1.  Unlicensed and off label prescription of drugs to children: population based cohort study.

Authors:  Geert W 'T Jong; Ingo A Eland; Miriam C J M Sturkenboom; John N van den Anker; Bruno H Ch Stricker
Journal:  BMJ       Date:  2002-06-01

2.  Off label prescribing to children in primary care in Germany: retrospective cohort study.

Authors:  Reinhild Bücheler; Matthias Schwab; Klaus Mörike; Bernhard Kalchthaler; Hartmut Mohr; Helmut Schröder; Peter Schwoerer; Christoph H Gleiter
Journal:  BMJ       Date:  2002-06-01

3.  Unlicensed and off label drug use by children in the community: cross sectional study.

Authors:  Eric Schirm; Hilde Tobi; Lolkje T W de Jong-van den Berg
Journal:  BMJ       Date:  2002-06-01

4.  Off-label prescribing to children in primary care: retrospective observational study.

Authors:  Suzie Ekins-Daukes; Peter J Helms; Colin R Simpson; Michael W Taylor; James S McLay
Journal:  Eur J Clin Pharmacol       Date:  2004-05-14       Impact factor: 2.953

Review 5.  Off licence and off label prescribing in children: litigation fears for physicians.

Authors:  P Hill
Journal:  Arch Dis Child       Date:  2005-02       Impact factor: 3.791

6.  The National Service Framework for children, young people and maternity services: developing the evidence base.

Authors:  P Sloper; J Statham
Journal:  Child Care Health Dev       Date:  2004-11       Impact factor: 2.508

7.  An academic, pharmaceutical and practice collaboration to implement asthma guidelines.

Authors:  Colin McCowan; Ron G Neville; Gaylor Hoskins
Journal:  Prim Care Respir J       Date:  2005-04

8.  Worldwide variations in the prevalence of asthma symptoms: the International Study of Asthma and Allergies in Childhood (ISAAC)

Authors: 
Journal:  Eur Respir J       Date:  1998-08       Impact factor: 16.671

9.  Widespread off-label prescribing of topical but not systemic drugs for 350,000 paediatric outpatients in Stockholm.

Authors:  Mike Ufer; Anders Rane; Ake Karlsson; Elin Kimland; Ulf Bergman
Journal:  Eur J Clin Pharmacol       Date:  2003-02-22       Impact factor: 2.953
  9 in total
  3 in total

1.  Current challenges in asthma.

Authors:  Christopher J Cates
Journal:  Br J Gen Pract       Date:  2007-03       Impact factor: 5.386

2.  Prescribing patterns of asthma controller therapy for children in UK primary care: a cross-sectional observational study.

Authors:  Mike Thomas; Tarita Murray-Thomas; Tao Fan; Tim Williams; Stephanie Taylor
Journal:  BMC Pulm Med       Date:  2010-05-14       Impact factor: 3.317

3.  Utilisation and off-label prescriptions of respiratory drugs in children.

Authors:  Sven Schmiedl; Rainald Fischer; Luisa Ibáñez; Joan Fortuny; Olaf H Klungel; Robert Reynolds; Roman Gerlach; Martin Tauscher; Petra Thürmann; Joerg Hasford; Marietta Rottenkolber
Journal:  PLoS One       Date:  2014-09-02       Impact factor: 3.240
  3 in total

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