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Literature DB >> 17358074

Synthesis of carbamates and ureas using Zr(IV)-catalyzed exchange processes.

Abstract

[reaction: see text] Zirconium(IV)-catalyzed exchange processes have been developed to prepare both carbamates and ureas from dialkyl carbonates and carbamates employing 2-hydroxypyridine (HYP) and 4-methyl-2-hydroxyquinoline (MeHYQ) as catalytic additives, respectively. A microwave acceleration effect was observed in Zr(IV)-catalyzed carbamate-urea exchange.

Entities: Chemical

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Year: 2007 PMID： 17358074 DOI： 10.1021/ol0702728

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

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Cited

6 in total

1. Synthesis of unsymmetrical diarylureas via Pd-catalyzed C-N cross-coupling reactions.

Authors: Simon Breitler; Nathan J Oldenhuis; Brett P Fors; Stephen L Buchwald
Journal: Org Lett Date: 2011-05-23 Impact factor: 6.005

2. Preparation and biological evaluation of synthetic and polymer-encapsulated congeners of the antitumor agent pactamycin: insight into functional group effects and biological activity.

Authors: Robert J Sharpe; Justin T Malinowski; Federico Sorana; J Christopher Luft; Charles J Bowerman; Joseph M DeSimone; Jeffrey S Johnson
Journal: Bioorg Med Chem Date: 2015-02-21 Impact factor: 3.641

Synthesis of carbamates and ureas using Zr(IV)-catalyzed exchange processes.

1. Synthesis of unsymmetrical diarylureas via Pd-catalyzed C-N cross-coupling reactions.

2. Preparation and biological evaluation of synthetic and polymer-encapsulated congeners of the antitumor agent pactamycin: insight into functional group effects and biological activity.

3. An intramolecular inverse electron demand Diels-Alder approach to annulated α-carbolines.

Review 4. Organic carbamates in drug design and medicinal chemistry.

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Review 6. DNA-encoded libraries (DELs): a review of on-DNA chemistries and their output.