BACKGROUND: Children with hydrocephalus represent a heterogeneous group with various aetiologies and disability profiles. Over the years, continuous changes in medical care have occurred and updated information is important. AIM: To study disability profiles in aetiological and gestational age subgroups of children with hydrocephalus in the 1990s. METHOD: A population-based series of 114 children, 70 with infantile hydrocephalus and 44 with hydrocephalus associated with MMC. All the children were examined clinically and interviewed. RESULTS: Learning disabilities were present in 47 % of children with infantile hydrocephalus compared with 16 % of those with MMC, cerebral palsy in 27 % vs. zero and epilepsy in 34 vs. 11 %. Even after excluding children with cerebral palsy, the majority had abnormal tendon reflexes and scored below the 5th centile on a motor test. Hydrocephalus overt at birth, low gestational age, a perinatal origin, enlarged ventricles at follow-up and several shunt revisions all indicated risk factors for a poor outcome. CONCLUSIONS: In spite of major advances in management, hydrocephalus in children still has a considerable impact on outcome. Being born very preterm and with a hydrocephalus that is already overt at birth involve the highest risk of a poor outcome. Apart from major impairments, the children frequently have definite motor problems.
BACKGROUND:Children with hydrocephalus represent a heterogeneous group with various aetiologies and disability profiles. Over the years, continuous changes in medical care have occurred and updated information is important. AIM: To study disability profiles in aetiological and gestational age subgroups of children with hydrocephalus in the 1990s. METHOD: A population-based series of 114 children, 70 with infantile hydrocephalus and 44 with hydrocephalus associated with MMC. All the children were examined clinically and interviewed. RESULTS:Learning disabilities were present in 47 % of children with infantile hydrocephalus compared with 16 % of those with MMC, cerebral palsy in 27 % vs. zero and epilepsy in 34 vs. 11 %. Even after excluding children with cerebral palsy, the majority had abnormal tendon reflexes and scored below the 5th centile on a motor test. Hydrocephalus overt at birth, low gestational age, a perinatal origin, enlarged ventricles at follow-up and several shunt revisions all indicated risk factors for a poor outcome. CONCLUSIONS: In spite of major advances in management, hydrocephalus in children still has a considerable impact on outcome. Being born very preterm and with a hydrocephalus that is already overt at birth involve the highest risk of a poor outcome. Apart from major impairments, the children frequently have definite motor problems.
Authors: Phan Q Duy; Stefan C Weise; Claudia Marini; Xiao-Jun Li; Dan Liang; Peter J Dahl; Shaojie Ma; Ana Spajic; Weilai Dong; Jane Juusola; Emre Kiziltug; Adam J Kundishora; Sunil Koundal; Maysam Z Pedram; Lucia A Torres-Fernández; Kristian Händler; Elena De Domenico; Matthias Becker; Thomas Ulas; Stefan A Juranek; Elisa Cuevas; Le Thi Hao; Bettina Jux; André M M Sousa; Fuchen Liu; Suel-Kee Kim; Mingfeng Li; Yiying Yang; Yutaka Takeo; Alvaro Duque; Carol Nelson-Williams; Yonghyun Ha; Kartiga Selvaganesan; Stephanie M Robert; Amrita K Singh; Garrett Allington; Charuta G Furey; Andrew T Timberlake; Benjamin C Reeves; Hannah Smith; Ashley Dunbar; Tyrone DeSpenza; June Goto; Arnaud Marlier; Andres Moreno-De-Luca; Xin Yu; William E Butler; Bob S Carter; Evelyn M R Lake; R Todd Constable; Pasko Rakic; Haifan Lin; Engin Deniz; Helene Benveniste; Nikhil S Malvankar; Juvianee I Estrada-Veras; Christopher A Walsh; Seth L Alper; Joachim L Schultze; Katrin Paeschke; Angelika Doetzlhofer; F Gregory Wulczyn; Sheng Chih Jin; Richard P Lifton; Nenad Sestan; Waldemar Kolanus; Kristopher T Kahle Journal: Nat Neurosci Date: 2022-04-04 Impact factor: 28.771
Authors: Weihong Yuan; Scott K Holland; Joshua S Shimony; Mekibib Altaye; Francesco T Mangano; David D Limbrick; Blaise V Jones; Tiffany Nash; Akila Rajagopal; Sarah Simpson; Dustin Ragan; Robert C McKinstry Journal: Neuroimage Clin Date: 2015-04-29 Impact factor: 4.881
Authors: Kelley E Deren; Jennifer Forsyth; Osama Abdullah; Edward W Hsu; Petra M Klinge; Gerald D Silverberg; Conrad E Johanson; James P McAllister Journal: Cerebrospinal Fluid Res Date: 2009-05-26