Literature DB >> 17356784

Dynamic kinetic resolution of 2-oxo-3-aryl-succinates by organocatalyzed aldolization.

Yajun Wang1, Zongxuan Shen, Bin Li, Yong Zhang, Yawen Zhang.   

Abstract

The dynamic kinetic resolution of 2-oxo-3-arylsuccinates was achieved vial-proline-catalyzed addition of acetone in acetonitrile at room temperature, providing the desired adduct in good yield with up to 87 : 13 dr and high ee up to 99%.

Entities:  

Year:  2007        PMID: 17356784     DOI: 10.1039/b616382c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Asymmetric Synthesis of β-Amino Amides by Catalytic Enantioconvergent 2-Aza-Cope Rearrangement.

Authors:  C Guy Goodman; Jeffrey S Johnson
Journal:  J Am Chem Soc       Date:  2015-11-12       Impact factor: 15.419

2.  Dynamic kinetic asymmetric transformations of β-stereogenic α-ketoesters by direct aldolization.

Authors:  Michael T Corbett; Jeffrey S Johnson
Journal:  Angew Chem Int Ed Engl       Date:  2013-11-12       Impact factor: 15.336

  2 in total

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