Literature DB >> 17356615

Chemical concentration measurement in blood serum and urine samples using liquid-core optical fiber Raman spectroscopy.

Dahu Qi1, Andrew J Berger.   

Abstract

We report measurements of chemical concentrations in clinical blood serum and urine samples using liquid-core optical fiber (LCOF) Raman spectroscopy to increase the collected signal strength. Both Raman and absorption spectra were acquired in the near-infrared region using the LCOF geometry. Spectra of 71 blood serum and 61 urine samples were regressed via partial least squares against reference analyzer values. Significant correlation was found between predicted and reference concentrations for 13 chemicals. Using absorption data to normalize the LCOF enhancement made the results more accurate. The experimental geometry is well suited for high-volume and automated chemical analysis of clear biofluids.

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Year:  2007        PMID： 17356615     DOI： 10.1364/ao.46.001726

Source DB:  PubMed          Journal:  Appl Opt        ISSN： 1559-128X            Impact factor:   1.980


  22 in total

1.  Estimating the concentration of urea and creatinine in the human serum of normal and dialysis patients through Raman spectroscopy.

Authors:  Maurício Liberal de Almeida; Cassiano Junior Saatkamp; Adriana Barrinha Fernandes; Antonio Luiz Barbosa Pinheiro; Landulfo Silveira
Journal:  Lasers Med Sci       Date:  2016-07-08       Impact factor: 3.161

2.  Rejection of fluorescence background in resonance and spontaneous Raman microspectroscopy.

Authors:  Zachary J Smith; Florian Knorr; Cynthia V Pagba; Sebastian Wachsmann-Hogiu
Journal:  J Vis Exp       Date:  2011-05-18       Impact factor: 1.355

3.  Spatially offset Raman spectroscopy for in vivo bone strength prediction.

Authors:  Chi Shu; Keren Chen; Maria Lynch; Jason R Maher; Hani A Awad; Andrew J Berger
Journal:  Biomed Opt Express       Date:  2018-09-12       Impact factor: 3.732

4.  Development of robust calibration models using support vector machines for spectroscopic monitoring of blood glucose.

Authors:  Ishan Barman; Chae-Ryon Kong; Narahara Chari Dingari; Ramachandra R Dasari; Michael S Feld
Journal:  Anal Chem       Date:  2010-11-04       Impact factor: 6.986

5.  Soft-tissue spectral subtraction improves transcutaneous Raman estimates of murine bone strength in vivo.

Authors:  Keren Chen; Christine Massie; Andrew J Berger
Journal:  J Biophotonics       Date:  2020-08-31       Impact factor: 3.207

6.  Quantifying glucose and lipid components in human serum by Raman spectroscopy and multivariate statistics.

Authors:  Landulfo Silveira; Rita de Cássia Fernandes Borges; Ricardo Scarparo Navarro; Hector Enrique Giana; Renato Amaro Zângaro; Marcos Tadeu Tavares Pacheco; Adriana Barrinha Fernandes
Journal:  Lasers Med Sci       Date:  2017-03-07       Impact factor: 3.161

7.  Investigation of the specificity of Raman spectroscopy in non-invasive blood glucose measurements.

Authors:  Narahara Chari Dingari; Ishan Barman; Gajendra P Singh; Jeon Woong Kang; Ramachandra R Dasari; Michael S Feld
Journal:  Anal Bioanal Chem       Date:  2011-04-21       Impact factor: 4.142

8.  Precision of Raman spectroscopy measurements in detection of microcalcifications in breast needle biopsies.

Authors:  Anushree Saha; Ishan Barman; Narahara Chari Dingari; Luis H Galindo; Abdus Sattar; Wendy Liu; Donna Plecha; Nina Klein; Ramachandra Rao Dasari; Maryann Fitzmaurice
Journal:  Anal Chem       Date:  2012-07-12       Impact factor: 6.986

Review 9.  Chemical analysis in vivo and in vitro by Raman spectroscopy--from single cells to humans.

Authors:  Sebastian Wachsmann-Hogiu; Tyler Weeks; Thomas Huser
Journal:  Curr Opin Biotechnol       Date:  2009-03-04       Impact factor: 9.740

10.  Evaluation of accuracy dependence of Raman spectroscopic models on the ratio of calibration and validation points for non-invasive glucose sensing.

Authors:  Surya P Singh; Soumavo Mukherjee; Luis H Galindo; Peter T C So; Ramachandra Rao Dasari; Uzma Zubair Khan; Raghuraman Kannan; Anandhi Upendran; Jeon Woong Kang
Journal:  Anal Bioanal Chem       Date:  2018-07-25       Impact factor: 4.142
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