Literature DB >> 1735601

Sister chromatid exchanges and chromosome aberrations in lymphocytes of nurses handling antineoplastic drugs.

E M Goloni-Bertollo1, E H Tajara, A J Manzato, M Varella-Garcia.   

Abstract

Chromosomal aberrations (CA) and sister-chromatid exchanges (SCE) were investigated in peripheral lymphocytes of 15 nurses and nurse's aides handling cytostatic agents in hospital oncology units. Significantly increased frequencies were noted for both CA and SCE rates when the exposed individuals were compared with 15 nurses working in other hospital units and to a control sample matched by sex and age. This points to the need for emphasizing protective measures in the handling of anti-neoplastic agents.

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Year:  1992        PMID： 1735601     DOI： 10.1002/ijc.2910500302

Source DB:  PubMed          Journal:  Int J Cancer        ISSN： 0020-7136            Impact factor:   7.396


  4 in total

1.  Inhalation and dermal exposure to eight antineoplastic drugs in an industrial laundry facility.

Authors:  Wouter Fransman; Daan Huizer; Jochen Tuerk; Hans Kromhout
Journal:  Int Arch Occup Environ Health       Date:  2006-10-05       Impact factor: 3.015

2.  Dermal exposure to cyclophosphamide in hospitals during preparation, nursing and cleaning activities.

Authors:  Wouter Fransman; Roel Vermeulen; Hans Kromhout
Journal:  Int Arch Occup Environ Health       Date:  2005-05-11       Impact factor: 3.015

Review 3.  Meta-analysis of chromosomal aberrations as a biomarker of exposure in healthcare workers occupationally exposed to antineoplastic drugs.

Authors:  Christine Roussel; Kristine L Witt; Peter B Shaw; Thomas H Connor
Journal:  Mutat Res Rev Mutat Res       Date:  2017-08-24       Impact factor: 5.657

4.  A study protocol for the evaluation of occupational mutagenic/carcinogenic risks in subjects exposed to antineoplastic drugs: a multicentric project.

Authors:  Massimo Moretti; Roberta Bonfiglioli; Donatella Feretti; Sofia Pavanello; Francesca Mussi; Maria G Grollino; Milena Villarini; Anna Barbieri; Elisabetta Ceretti; Mariella Carrieri; Annamaria Buschini; Massimo Appolloni; Luca Dominici; Laura Sabatini; Umberto Gelatti; Giovanni B Bartolucci; Paola Poli; Laura Stronati; Giuseppe Mastrangelo; Silvano Monarca
Journal:  BMC Public Health       Date:  2011-03-30       Impact factor: 3.295
  4 in total

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