Literature DB >> 17355478

Motor development in school-aged children with 22q11 deletion (velocardiofacial/DiGeorge syndrome).

Katrijn Van Aken1, Bert De Smedt, Annelies Van Roie, Marc Gewillig, Koen Devriendt, Jean-Pierre Fryns, Johan Simons, Ann Swillen.   

Abstract

The aim of this study was to compare the motor development of primary school children (age 5-14y) with a 22q11 deletion (del22q11) group and a control group. The effects of a congenital heart defect (CHD) and IQ on motor development were additionally studied within the del22q11 group. Motor development of 37 children with a del22q11 (20 males, 17 females; mean age 9y 4mo, range 5y 9mo-13y 3mo) and 34 controls (23 males, 11 females; mean age 9y 1mo, range 4y 8mo-13y 6mo) was assessed with the Bruininks-Oseretsky Test of Motor Proficiency. The del22q11 group showed a significant deficit in motor functioning compared with the control group (p < 0.01). Within the del22q11 group there was a significant effect of IQ on motor performance, but no effect of CHD was found. To conclude, primary school children with a del22q11 syndrome showed a significant deficit in motor performance compared with a control group. A significant effect of IQ on motor performance in del22q11 was found.

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Year:  2007        PMID: 17355478     DOI: 10.1111/j.1469-8749.2007.00210.x

Source DB:  PubMed          Journal:  Dev Med Child Neurol        ISSN: 0012-1622            Impact factor:   5.449


  11 in total

1.  22q11.2 deletion syndrome: are motor deficits more than expected for IQ level?

Authors:  Nancy J Roizen; Anne M Higgins; Kevin M Antshel; Wanda Fremont; Robert Shprintzen; Wendy R Kates
Journal:  J Pediatr       Date:  2010-06-19       Impact factor: 4.406

2.  Quality of life among children with velocardiofacial syndrome.

Authors:  Wendy S Looman; Anna K Thurmes; Susan K O'Conner-Von
Journal:  Cleft Palate Craniofac J       Date:  2010-05

3.  Prodromal symptoms in adolescents with 22q11.2 deletion syndrome and schizotypal personality disorder.

Authors:  D I Shapiro; J F Cubells; O Y Ousley; K Rockers; E F Walker
Journal:  Schizophr Res       Date:  2011-04-19       Impact factor: 4.939

4.  Contribution of congenital heart disease to neuropsychiatric outcome in school-age children with 22q11.2 deletion syndrome.

Authors:  James J Yi; Sunny X Tang; Donna M McDonald-McGinn; Monica E Calkins; Daneen A Whinna; Margaret C Souders; Elaine H Zackai; Elizabeth Goldmuntz; James W Gaynor; Ruben C Gur; Beverly S Emanuel; Raquel E Gur
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2013-11-22       Impact factor: 3.568

5.  Molecular screening for 22Q11.2 deletion syndrome in patients with congenital heart disease.

Authors:  Janaína Huber; Vivian Catarino Peres; Alexandre Luz de Castro; Tiago Jeronimo dos Santos; Lauro da Fontoura Beltrão; Angélica Cerveira de Baumont; Silvia Liliana Cossio; Tiago Pires Dalberto; Mariluce Riegel; Andrés Delgado Cañedo; Beatriz D'Agord Schaan; Lucia Campos Pellanda
Journal:  Pediatr Cardiol       Date:  2014-06-01       Impact factor: 1.655

6.  Histology of the pharyngeal constrictor muscle in 22q11.2 deletion syndrome and non-syndromic children with velopharyngeal insufficiency.

Authors:  Josine C C Widdershoven; Nicole E Spruijt; Wim G M Spliet; Corstiaan C Breugem; Moshe Kon; Aebele B Mink van der Molen
Journal:  PLoS One       Date:  2011-06-28       Impact factor: 3.240

7.  Abnormal gait, reduced locomotor activity and impaired motor coordination in Dgcr2-deficient mice.

Authors:  Shin-Ichiro Mugikura; Akira Katoh; Satoshi Watanabe; Minoru Kimura; Kagemasa Kajiwara
Journal:  Biochem Biophys Rep       Date:  2015-11-18

Review 8.  What's missing in autism spectrum disorder motor assessments?

Authors:  Rujuta B Wilson; James T McCracken; Nicole J Rinehart; Shafali S Jeste
Journal:  J Neurodev Disord       Date:  2018-12-13       Impact factor: 4.025

9.  Developmental coordination disorder, psychopathology and IQ in 22q11.2 deletion syndrome.

Authors:  Adam C Cunningham; Sue Delport; Wendy Cumines; Monica Busse; David E J Linden; Jeremy Hall; Michael J Owen; Marianne B M van den Bree
Journal:  Br J Psychiatry       Date:  2018-01       Impact factor: 10.671

10.  Variance of IQ is partially dependent on deletion type among 1,427 22q11.2 deletion syndrome subjects.

Authors:  Yingjie Zhao; Tingwei Guo; Ania Fiksinski; Elemi Breetvelt; Donna M McDonald-McGinn; Terrence B Crowley; Alexander Diacou; Maude Schneider; Stephan Eliez; Ann Swillen; Jeroen Breckpot; Joris Vermeesch; Eva W C Chow; Doron Gothelf; Sasja Duijff; Rens Evers; Thérèse A van Amelsvoort; Marianne van den Bree; Michael Owen; Maria Niarchou; Carrie E Bearden; Claudia Ornstein; Maria Pontillo; Antonino Buzzanca; Stefano Vicari; Marco Armando; Kieran C Murphy; Clodagh Murphy; Sixto Garcia-Minaur; Nicole Philip; Linda Campbell; Jaume Morey-Cañellas; Jasna Raventos; Jordi Rosell; Damian Heine-Suner; Robert J Shprintzen; Raquel E Gur; Elaine Zackai; Beverly S Emanuel; Tao Wang; Wendy R Kates; Anne S Bassett; Jacob A S Vorstman; Bernice E Morrow
Journal:  Am J Med Genet A       Date:  2018-10-05       Impact factor: 2.802

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