Literature DB >> 17353477

High CSF neurofilament heavy chain levels in neuromyelitis optica.

I Miyazawa1, I Nakashima, A Petzold, K Fujihara, S Sato, Y Itoyama.   

Abstract

The neurofilament heavy chain (NfHSMI35), a biomarker of axonal damage in the CSF, was measured in patients with neuromyelitis optica (NMO) and multiple sclerosis (MS). Significantly high CSF NfHSMI35 levels (>0.73 ng/mL) were found in 6 of 24 (25%) of the patients with NMO but none of the patients with MS (0/24). This finding suggests that axonal damage is more severe in NMO than in MS.

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Year:  2007        PMID： 17353477     DOI： 10.1212/01.wnl.0000256820.26489.17

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  13 in total

1.  Early high-dose intravenous methylprednisolone is effective in preserving retinal nerve fiber layer thickness in patients with neuromyelitis optica.

Authors:  Masahiko Nakamura; Toru Nakazawa; Hiroshi Doi; Takehiro Hariya; Kazuko Omodaka; Tatsuro Misu; Toshiyuki Takahashi; Kazuo Fujihara; Kohji Nishida
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2010-03-19       Impact factor: 3.117

2.  Increased radial diffusivity in spinal cord lesions in neuromyelitis optica compared with multiple sclerosis.

Authors:  Eric C Klawiter; Junqian Xu; Robert T Naismith; Tammie L S Benzinger; Joshua S Shimony; Samantha Lancia; Abraham Z Snyder; Kathryn Trinkaus; Sheng-Kwei Song; Anne H Cross
Journal:  Mult Scler       Date:  2012-02-21       Impact factor: 6.312

Review 3.  AQP4 antibodies in neuromyelitis optica: diagnostic and pathogenetic relevance.

Authors:  Sven Jarius; Brigitte Wildemann
Journal:  Nat Rev Neurol       Date:  2010-07       Impact factor: 42.937

4.  Proteome analysis of haptoglobin in cerebrospinal fluid of neuromyelitis optica.

Authors:  Shumei Bai; Shilian Liu; Xuxiao Guo; Zhaoyu Qin; Banqin Wang; Xiaohong Li; Yanjiang Qin
Journal:  Mol Biol Rep       Date:  2009-05-15       Impact factor: 2.316

Review 5.  Disease biomarkers in multiple sclerosis: potential for use in therapeutic decision making.

Authors:  Violaine K Harris; Saud A Sadiq
Journal:  Mol Diagn Ther       Date:  2009       Impact factor: 4.074

6.  Association of neuromyelitis optica with severe and intractable pain.

Authors:  Peiqing Qian; Samantha Lancia; Enrique Alvarez; Eric C Klawiter; Anne H Cross; Robert T Naismith
Journal:  Arch Neurol       Date:  2012-11

Review 7.  Neurofilaments: neurobiological foundations for biomarker applications.

Authors:  Arie R Gafson; Nicolas R Barthélemy; Pascale Bomont; Roxana O Carare; Heather D Durham; Jean-Pierre Julien; Jens Kuhle; David Leppert; Ralph A Nixon; Roy O Weller; Henrik Zetterberg; Paul M Matthews
Journal:  Brain       Date:  2020-07-01       Impact factor: 13.501

8.  Cerebrospinal fluid and blood biomarkers of neuroaxonal damage in multiple sclerosis.

Authors:  Irena Dujmovic
Journal:  Mult Scler Int       Date:  2011-05-02

9.  Proteome analysis of biomarkers in the cerebrospinal fluid of neuromyelitis optica patients.

Authors:  Shumei Bai; Shilian Liu; Xuxiao Guo; Zhaoyu Qin; Banqin Wang; Xiaohong Li; Yanjiang Qin; Yi-Hsin Liu
Journal:  Mol Vis       Date:  2009-08-19       Impact factor: 2.367

10.  The diagnostic and prognostic value of neurofilament heavy chain levels in immune-mediated optic neuropathies.

Authors:  Axel Petzold; Gordon T Plant
Journal:  Mult Scler Int       Date:  2012-12-17
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