Literature DB >> 17352487

Low-valent niobium-catalyzed reduction of alpha,alpha,alpha-trifluorotoluenes.

Kohei Fuchibe1, Yoshitaka Ohshima, Ken Mitomi, Takahiko Akiyama.   

Abstract

[reaction: see text] In the presence of 5 mol % of niobium(V) chloride, alpha,alpha,alpha-trifluorotoluene derivatives were reduced with lithium aluminum hydride to give toluene derivatives in good yields. Stepwise, partial reduction of bis(trifluoromethyl)benzene derivative was also demonstrated.

Entities:  

Year:  2007        PMID: 17352487     DOI: 10.1021/ol070249m

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  4 in total

1.  Selective C-F Functionalization of Unactivated Trifluoromethylarenes.

Authors:  David B Vogt; Ciaran P Seath; Hengbin Wang; Nathan T Jui
Journal:  J Am Chem Soc       Date:  2019-08-09       Impact factor: 15.419

2.  Photochemical C-F Activation Enables Defluorinative Alkylation of Trifluoroacetates and -Acetamides.

Authors:  Mark W Campbell; Viktor C Polites; Shivani Patel; Juliette E Lipson; Jadab Majhi; Gary A Molander
Journal:  J Am Chem Soc       Date:  2021-11-18       Impact factor: 16.383

3.  Ethylenation of aldehydes to 3-propanal, propanol and propanoic acid derivatives.

Authors:  Daniel T Payne; Yiming Zhao; John S Fossey
Journal:  Sci Rep       Date:  2017-05-11       Impact factor: 4.379

4.  Catalytic activation of a single C-F bond in trifluoromethyl arenes.

Authors:  Hester Dang; Aaron M Whittaker; Gojko Lalic
Journal:  Chem Sci       Date:  2015-10-23       Impact factor: 9.825

  4 in total

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