PURPOSE OF REVIEW: The purpose is to review recent papers on the prognosis of epilepsy, with an emphasis on the importance of considering the temporal aspects of epilepsy. RECENT FINDINGS: The review considers five specific points: What is the chance of spontaneous remission without treatment (i.e. what is the natural history of untreated epilepsy)? What is the prognosis of epilepsy in newly diagnosed patients and how effective is therapy in previously drug-naïve patients? Does delaying treatment make long-term prognosis worse? Is the prognosis of chronic established epilepsy inevitably bad? Refractory epilepsy, pharmaco-resistance and the influence of time. SUMMARY: This paper reviews the recent evidence that has provided data about temporal aspects of prognosis in epilepsy and confirms the importance of taking a synoptical view of prognosis, incorporating temporal aspects, in making clinical prognostic predictions.
PURPOSE OF REVIEW: The purpose is to review recent papers on the prognosis of epilepsy, with an emphasis on the importance of considering the temporal aspects of epilepsy. RECENT FINDINGS: The review considers five specific points: What is the chance of spontaneous remission without treatment (i.e. what is the natural history of untreated epilepsy)? What is the prognosis of epilepsy in newly diagnosed patients and how effective is therapy in previously drug-naïve patients? Does delaying treatment make long-term prognosis worse? Is the prognosis of chronic established epilepsy inevitably bad? Refractory epilepsy, pharmaco-resistance and the influence of time. SUMMARY: This paper reviews the recent evidence that has provided data about temporal aspects of prognosis in epilepsy and confirms the importance of taking a synoptical view of prognosis, incorporating temporal aspects, in making clinical prognostic predictions.
Authors: Angelo Labate; Antonio Gambardella; Eva Andermann; Umberto Aguglia; Fernando Cendes; Samuel F Berkovic; Frederick Andermann Journal: Nat Rev Neurol Date: 2011-01-25 Impact factor: 42.937
Authors: Sofie F M Bhatti; Luisa De Risio; Karen Muñana; Jacques Penderis; Veronika M Stein; Andrea Tipold; Mette Berendt; Robyn G Farquhar; Andrea Fischer; Sam Long; Wolfgang Löscher; Paul J J Mandigers; Kaspar Matiasek; Akos Pakozdy; Edward E Patterson; Simon Platt; Michael Podell; Heidrun Potschka; Clare Rusbridge; Holger A Volk Journal: BMC Vet Res Date: 2015-08-28 Impact factor: 2.741