Literature DB >> 17350198

Early diagnosis of Wegener's granulomatosis presenting with bilateral facial paralysis and bilateral serous otitis media.

Emanuele Ferri1, Enrico Armato, Paolo Capuzzo, Stefano Cavaleri, Ferdinando Ianniello.   

Abstract

Wegener's granulomatosis (WG) is a multi-system disease characterized by granuloma formation and widespread necrotizing vasculitis. It classically presents with involvement of the upper and lower respiratory tracts and renal system. Facial nerve palsy and otologic manifestations have been reported during the course of the disease but it is extremely rare as the presenting features. In Literature only one case of bilateral facial palsy as presenting sign of WG is reported. The testing of anticytoplasmic antibodies versus neutrophil polymorphonucleate granules (c-ANCA) are highly specific for the diagnosis of WG, being positive in 97% of the cases. The early diagnosis and the timely medical treatment lead to high rates of remission of an otherwise lethal disease. A case of WG presenting with bilateral facial paralysis and bilateral serous otitis media is reported.

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Year:  2007        PMID: 17350198     DOI: 10.1016/j.anl.2007.01.005

Source DB:  PubMed          Journal:  Auris Nasus Larynx        ISSN: 0385-8146            Impact factor:   1.863


  10 in total

1.  [Bilateral deafness and unilateral facial nerve palsy as presenting features of Wegener's granulomatosis : a case report].

Authors:  S Bohne; S Koscielny; H P Burmeister; O Guntinas-Lichius; C Wittekindt
Journal:  HNO       Date:  2010-05       Impact factor: 1.284

2.  Pathways to renal biopsy and diagnosis among patients with ANCA small-vessel vasculitis.

Authors:  C J Poulton; P H Nachman; Y Hu; J G McGregor; J C Jennette; R J Falk; S L Hogan
Journal:  Clin Exp Rheumatol       Date:  2013-01-23       Impact factor: 4.473

3.  Intractable chronic otitis media, rhinosinusitis and facial palsy: a case of active granulomatosis with polyangiitis.

Authors:  Kwee Yen Goh; Ross Bannon; Helin Nie Darat; Bhaskar Ram; Raghav C Dwivedi
Journal:  BMJ Case Rep       Date:  2020-09-07

4.  Granulomatosis with Polyangiitis with Bilateral Facial Palsy and Severe Mixed Hearing Loss.

Authors:  Agnieszka Wawrzecka; Anna Szymańska; Radosław Jeleniewicz; Marcin Szymański
Journal:  Case Rep Otolaryngol       Date:  2016-07-14

5.  Internal Auditory Canal Dural Enhancement in Granulomatosis with Polyangeitis Disease.

Authors:  Juan Carlos Izquierdo Velásquez; Luis Felipe Romero Moreno
Journal:  Case Rep Neurol Med       Date:  2018-05-21

6.  Bilateral facial palsy in rapidly progressive course of Wegener's granulomatosis: a case report.

Authors:  Anna Roszkowska; Monika Morawska-Kochman; Hanna Temporale; Małgorzata Sikorska-Żuk; Tomasz Kręcicki
Journal:  Case Rep Otolaryngol       Date:  2013-09-25

7.  Refractory Granulomatosis with Polyangiitis Presenting as Facial Paralysis and Bilateral Sudden Deafness.

Authors:  Sang Hoon Kim; A Ra Jung; Su Il Kim; Seung Geun Yeo
Journal:  J Audiol Otol       Date:  2016-04-21

8.  A Case of Wegener's Granulomatosis Presenting with Unilateral Facial Nerve Palsy.

Authors:  Roy Ujjawal; Pan Koushik; Panwar Ajay; Chakrabarti Subrata
Journal:  Case Rep Med       Date:  2016-03-24

9.  Granulomatosis with polyangiitis: a 17 year experience from a tertiary care hospital in Pakistan.

Authors:  Omar Irfan; Haris Khan; Zarrar Khan; Alina Ashraf; Rimsha Ahmed; Javaid Ahmad Khan; Ali Bin Sarwar Zubairi
Journal:  BMC Res Notes       Date:  2018-05-16

10.  Refractory otitis media as the first manifestation of Wegener's granulomatosis.

Authors:  Bruno Almeida Antunes Rossini; Eduardo Amaro Bogaz; Fernando Kaoru Yonamine; José Ricardo Gurgel Testa; Norma de Oliveira Penido
Journal:  Braz J Otorhinolaryngol       Date:  2010 Jul-Aug
  10 in total

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