Literature DB >> 1734896

Potassium channels in nervous tissue.

J K Aronson1.   

Abstract

There is a multiplicity of potassium channels in nervous tissue. These have been characterized on the basis of their electrophysiological actions but more information is required on their structures and on the functions of the different subtypes of channel in different parts of the nervous system. We currently also lack drugs which are specific in opening or closing individual subtypes of channel. However, when more is known about the structure and function of these channels and when more specific modulators of their activity are available, it is likely that the use of such compounds may be of great value in the treatment of a variety of conditions affecting the nervous system, including epilepsy, the damage due to cerebral anoxia, neurodegenerative disorders and demyelinating disorders.

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Year:  1992        PMID: 1734896     DOI: 10.1016/0006-2952(92)90653-z

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN: 0006-2952            Impact factor:   5.858


  8 in total

1.  Mobilization of calcium from intracellular stores, potentiation of neurotransmitter-induced calcium transients, and capacitative calcium entry by 4-aminopyridine.

Authors:  M Grimaldi; M Atzori; P Ray; D L Alkon
Journal:  J Neurosci       Date:  2001-05-01       Impact factor: 6.167

2.  Effect of potassium channel modulators in mouse forced swimming test.

Authors:  N Galeotti; C Ghelardini; B Caldari; A Bartolini
Journal:  Br J Pharmacol       Date:  1999-04       Impact factor: 8.739

3.  Methylamine and benzylamine induced hypophagia in mice: modulation by semicarbazide-sensitive benzylamine oxidase inhibitors and aODN towards Kv1.1 channels.

Authors:  R Pirisino; C Ghelardini; G Banchelli; N Galeotti; L Raimondi
Journal:  Br J Pharmacol       Date:  2001-10       Impact factor: 8.739

4.  Imipramine inhibition of transient K+ current: an external open channel blocker preventing fast inactivation.

Authors:  C C Kuo
Journal:  Biophys J       Date:  1998-12       Impact factor: 4.033

5.  Role of potassium channels in the antinociception induced by agonists of alpha2-adrenoceptors.

Authors:  N Galeotti; C Ghelardini; M C Vinci; A Bartolini
Journal:  Br J Pharmacol       Date:  1999-03       Impact factor: 8.739

6.  Dendrotoxin blocks a class of potassium channels that are opened by inhibitory presynaptic modulators in rat cortical synaptosomes and slices.

Authors:  G Zoltay; J R Cooper
Journal:  Cell Mol Neurobiol       Date:  1993-02       Impact factor: 5.046

7.  Lack of effect of potassium channel openers on ATP-modulated potassium channels recorded from rat ventromedial hypothalamic neurones.

Authors:  A J Sellers; P R Boden; M L Ashford
Journal:  Br J Pharmacol       Date:  1992-12       Impact factor: 8.739

8.  Differential effects of K+ channel blockers on antinociception induced by alpha 2-adrenoceptor, GABAB and kappa-opioid receptor agonists.

Authors:  M Ocaña; J M Baeyens
Journal:  Br J Pharmacol       Date:  1993-11       Impact factor: 8.739

  8 in total

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