Literature DB >> 17348607

[The use of triptan in ambulatory medicine in Midi-Pyrénées Region: clinical and pharmacological contra-indications and drug abuse].

Henri Roussel1, Geneviève Lo Re, Christian Honorat, Michèle Alonso, Vincent Sciortino.   

Abstract

OBJECTIVE: Evaluate triptan prescriptions in ambulatory medicine.
METHODS: Collection of medical data from 301 patients treated with triptans reimbursed by the French National Health Fund in the region of Midi-Pyrenees.
RESULTS: Ninety-five per cent of selected patients suffered from migraine condition according to the International Headache Society diagnosis criteria [Confidence interval (CI) 95%: 93-98]. Co-morbidity factors contra-indicating triptan therapy were present in 6% of patients (CI 95%: 3-9). 2% of patients were prescribed other medicinal products contra-indicated with their triptan therapy (CI 95%: 0-4). Twenty-six per cent of patients were taking triptan medicines more than 8 times per month over a period of three months (CI 95%: 21-31) and 8% were taking this treatment more than 12 times per month (CI 95%: 5-1 I). Eleven per cent kept written information of their migraine crises (CI 95%: 7-15). Thirty-nine per cent benefited from dedicated prophylactic treatments (CI 95%: 33-45).
CONCLUSION: In a context of sustained increase in prescriptions of migraine treatments, it appears necessary to remain cautious about clinical and pharmacological contra-indications. Prevention of abuse of medicines is based on a better use of crises agendas and introduction of prophylactic therapies.

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Year:  2006        PMID: 17348607

Source DB:  PubMed          Journal:  Therapie        ISSN: 0040-5957            Impact factor:   2.070


  2 in total

1.  Triptans in the Italian population: a drug utilization study and a literature review.

Authors:  Alessandro Panconesi; Eleonora Pavone; Franca Vacca; Monica Vaiani; Roberto Banfi
Journal:  J Headache Pain       Date:  2008-03-04       Impact factor: 7.277

2.  Triptan use and risk of cardiovascular events: a nested-case-control study from the French health system database.

Authors:  S Lugardon; H Roussel; V Sciortino; J L Montastruc; M Lapeyre-Mestre
Journal:  Eur J Clin Pharmacol       Date:  2007-06-19       Impact factor: 3.064

  2 in total

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