Literature DB >> 17347863

Hypocalcemic tetany in the newborn as a manifestation of unrecognized maternal primary hyperparathyroidism.

Herwig Pieringer1, Margit Hatzl-Griesenhofer, Omar Shebl, Gabriele Wiesinger-Eidenberger, Wilhelmine Maschek, Georg Biesenbach.   

Abstract

Primary hyperparathyroidism (PHP) during pregnancy is a very rare event that increases maternal and perinatal morbidity and mortality. We present a case in which hypocalcemic tetany of the neonatal infant - caused by transient hypoparathyroidism in the child - finally revealed asymptomatic maternal PHP. An apparently healthy 30-year-old woman had an uneventful pregnancy and delivery. On the 15th postpartal day, the newborn developed hypocalcemic tetany. After receiving supplementation of calcium and vitamin D, the child developed without further pathological findings. Laboratory and radiological studies in the mother led to a diagnosis of maternal PHP. An adenoma of the right lower parathyroid gland was subsequently removed. The search for the cause of hypocalcemia in a newborn should not focus on the patient alone. Examining the apparently healthy mother and approaching the case in a multidisciplinary fashion may benefit both the child and the mother.

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Year:  2007        PMID: 17347863     DOI: 10.1007/s00508-006-0748-1

Source DB:  PubMed          Journal:  Wien Klin Wochenschr        ISSN: 0043-5325            Impact factor:   1.704


  24 in total

1.  Circulating levels of biologically active and immunoreactive intact parathyroid hormone in human newborns.

Authors:  L P Rubin; J T Posillico; C S Anast; E M Brown
Journal:  Pediatr Res       Date:  1991-02       Impact factor: 3.756

Review 2.  Hyperparathyroidism in pregnancy: diagnostic dilemma?

Authors:  J A Murray; W A Newman; J V Dacus
Journal:  Obstet Gynecol Surv       Date:  1997-03       Impact factor: 2.347

3.  Parathyroid hormone-related peptide (PTHrP) regulates fetal-placental calcium transport through a receptor distinct from the PTH/PTHrP receptor.

Authors:  C S Kovacs; B Lanske; J L Hunzelman; J Guo; A C Karaplis; H M Kronenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1996-12-24       Impact factor: 11.205

Review 4.  A systematic review of the diagnosis and treatment of primary hyperparathyroidism from 1995 to 2003.

Authors:  James M Ruda; Christopher S Hollenbeak; Brendan C Stack
Journal:  Otolaryngol Head Neck Surg       Date:  2005-03       Impact factor: 3.497

Review 5.  Role of the fetal parathyroid glands and parathyroid hormone-related protein in the regulation of placental transport of calcium, magnesium and inorganic phosphate.

Authors:  R J MacIsaac; J A Heath; C P Rodda; J M Moseley; A D Care; T J Martin; I W Caple
Journal:  Reprod Fertil Dev       Date:  1991       Impact factor: 2.311

6.  Calcium-regulating hormones and parathyroid hormone-related peptide in normal human pregnancy and postpartum: a longitudinal study.

Authors:  M S Ardawi; H A Nasrat; H S BA'Aqueel
Journal:  Eur J Endocrinol       Date:  1997-10       Impact factor: 6.664

7.  Primary hyperparathyroidism, pregnancy, and neonatal hypocalcemia.

Authors:  E L Kaplan; J D Burrington; P Klementschitsch; J Taylor; L Deftos
Journal:  Surgery       Date:  1984-10       Impact factor: 3.982

8.  Primary hyperparathyroidism in pregnancy--report of 3 cases.

Authors:  Y Y Hsieh; C C Chang; H D Tsai; T C Yang; T H Chiu; C H Tsai
Journal:  Arch Gynecol Obstet       Date:  1998       Impact factor: 2.344

9.  [Primary hyperparathyroidism and pregnancy. Aspects of neonatal morbidity].

Authors:  T Peschgens; C Stollbrink-Peschgens; U Merz; B Schneider; N Maurin; T Kutta; H Hörnchen
Journal:  Z Geburtshilfe Perinatol       Date:  1994 May-Jun

Review 10.  Primary hyperparathyroidism during pregnancy.

Authors:  T R Kelly
Journal:  Surgery       Date:  1991-12       Impact factor: 3.982

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  3 in total

1.  Transient neonatal hypoparathyroidism in two siblings unmasking maternal normocalcemic hyperparathyroidism.

Authors:  Preamrudee Poomthavorn; Boonsong Ongphiphadhanakul; Pat Mahachoklertwattana
Journal:  Eur J Pediatr       Date:  2007-06-15       Impact factor: 3.183

Review 2.  Parathyroid Disease in Pregnancy and Lactation: A Narrative Review of the Literature.

Authors:  Elena Tsourdi; Athanasios D Anastasilakis
Journal:  Biomedicines       Date:  2021-04-26

3.  Seventeen Cases of Primary Hyperparathyroidism in Pregnancy: A Call for Management Guidelines.

Authors:  Aimee Natasha DiMarco; Karim Meeran; Ioannis Christakis; Vinpreet Sodhi; Catherine Nelson-Piercy; Neil Samuel Tolley; Francesco Fausto Palazzo
Journal:  J Endocr Soc       Date:  2019-02-20
  3 in total

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