PURPOSE: The purpose of the study was to compare the quality of life (QoL), fatigue and mental distress in survivors of malignant extremity bone tumours (EBT survivors) with age and gender-matched survivors of Hodgkin's disease (HD survivors) and testicular cancer (TC survivors) as well as normative samples from the general population. PATIENTS AND METHODS: Five years or more after end of treatment, 75 EBT survivors were mailed a questionnaire containing Short Form-36 (SF-36), the Hospital Anxiety and Depression Scale, the Fatigue Questionnaire and questions about demography. Fifty-eight EBT survivors responded. TC survivors, HD survivors and normative samples (NORMs) had earlier on filled in the same questionnaire. For EBT survivors, gender and age-matched controls were randomly selected among TC survivors, HD survivors and NORMs. RESULTS: No significant differences in the fatigue or mental distress scores were observed between the survivor groups. The EBT survivors had significantly higher fatigue scores and lower depression scores than NORMs and significantly lower scores on all physical dimensions of QoL than TC survivors, HD survivors and NORMs. In multivariate analysis, a low level of education and lack of employment were significantly associated with caseness of mental distress. Older age at survey, female gender, being an EBT survivor and lack of employment were associated with caseness on the SF-36 Physical Component Summary Scale. CONCLUSION: At long-term follow-up, EBT survivors did not show impaired mental health or fatigue at the group level, although their post-treatment status was characterised by reduced QoL dimensions on physical function compared to TC survivors, HD survivors and NORMs.
PURPOSE: The purpose of the study was to compare the quality of life (QoL), fatigue and mental distress in survivors of malignant extremity bone tumours (EBT survivors) with age and gender-matched survivors of Hodgkin's disease (HD survivors) and testicular cancer (TC survivors) as well as normative samples from the general population. PATIENTS AND METHODS: Five years or more after end of treatment, 75 EBT survivors were mailed a questionnaire containing Short Form-36 (SF-36), the Hospital Anxiety and Depression Scale, the Fatigue Questionnaire and questions about demography. Fifty-eight EBT survivors responded. TC survivors, HD survivors and normative samples (NORMs) had earlier on filled in the same questionnaire. For EBT survivors, gender and age-matched controls were randomly selected among TC survivors, HD survivors and NORMs. RESULTS: No significant differences in the fatigue or mental distress scores were observed between the survivor groups. The EBT survivors had significantly higher fatigue scores and lower depression scores than NORMs and significantly lower scores on all physical dimensions of QoL than TC survivors, HD survivors and NORMs. In multivariate analysis, a low level of education and lack of employment were significantly associated with caseness of mental distress. Older age at survey, female gender, being an EBT survivor and lack of employment were associated with caseness on the SF-36 Physical Component Summary Scale. CONCLUSION: At long-term follow-up, EBT survivors did not show impaired mental health or fatigue at the group level, although their post-treatment status was characterised by reduced QoL dimensions on physical function compared to TC survivors, HD survivors and NORMs.
Authors: N J Lindner; O Ramm; A Hillmann; R Roedl; G Gosheger; C Brinkschmidt; H Juergens; W Winkelmann Journal: Clin Orthop Relat Res Date: 1999-01 Impact factor: 4.176
Authors: D B Greenberg; A Goorin; M C Gebhardt; L Gupta; N Stier; D Harmon; H Mankin Journal: Oncology (Williston Park) Date: 1994-11 Impact factor: 2.990
Authors: Melissa M Hudson; Ann C Mertens; Yutaka Yasui; Wendy Hobbie; Hegang Chen; James G Gurney; Mark Yeazel; Christopher J Recklitis; Neyssa Marina; Leslie R Robison; Kevin C Oeffinger Journal: JAMA Date: 2003-09-24 Impact factor: 157.335
Authors: Anna Spathis; Sara Booth; Sarah Grove; Helen Hatcher; Isla Kuhn; Stephen Barclay Journal: J Adolesc Young Adult Oncol Date: 2015-03 Impact factor: 2.223
Authors: Nadine Linendoll; Tully Saunders; Rebecca Burns; Jonathan D Nyce; Kristen B Wendell; Andrew M Evens; Susan K Parsons Journal: Health Qual Life Outcomes Date: 2016-07-29 Impact factor: 3.186
Authors: Anna Spathis; Helen Hatcher; Sara Booth; Faith Gibson; Paddy Stone; Laura Abbas; Matt Barclay; James Brimicombe; Pia Thiemann; Martin G McCabe; Rachel Campsey; Louise Hooker; Wendy Moss; Jane Robson; Stephen Barclay Journal: J Adolesc Young Adult Oncol Date: 2017-07-17 Impact factor: 2.223
Authors: Hanneke Poort; Suzanne E J Kaal; Hans Knoop; Rosemarie Jansen; Judith B Prins; Eveliene Manten-Horst; Petra Servaes; Olga Husson; Winette T A van der Graaf Journal: Support Care Cancer Date: 2017-05-20 Impact factor: 3.603