PURPOSE: The aim of this study was to compare the utility of baseline neuropsychological measures and scores from the intracarotid amobarbital procedure (IAP) in the prediction of postoperative memory decline in temporal lobe epilepsy surgery patients. METHODS: Logistic regression analyses were used to determine the relation between demographic variables, baseline neuropsychological scores, and scores from the IAP (using mixed verbal and nonverbal stimuli) and postoperative deterioration in verbal learning and verbal recall in 91 patients (48 right, RTL; 43 left, LTL) who had undergone a standard anterior temporal lobe resection for the relief of medically intractable epilepsy and who had been followed up 1 year postoperatively. RESULTS: In the RTL group, the IAP scores were not significant predictors of a postoperative decline in verbal learning or recall. In the LTL group, postoperative decline in verbal learning was associated with good preoperative baseline scores, an older age at the time of surgery, and an unexpected asymmetry on the IAP. Baseline neuropsychological scores and scores from the IAP were associated with a significant postoperative decline in verbal recall in the LTL group. CONCLUSIONS: Scores from the IAP using mixed stimuli were not helpful in the prediction of postoperative verbal memory decline in RTL patients. The significance of IAP scores in predicting verbal memory deficits in LTL patients may be task specific.
PURPOSE: The aim of this study was to compare the utility of baseline neuropsychological measures and scores from the intracarotid amobarbital procedure (IAP) in the prediction of postoperative memory decline in temporal lobe epilepsy surgery patients. METHODS: Logistic regression analyses were used to determine the relation between demographic variables, baseline neuropsychological scores, and scores from the IAP (using mixed verbal and nonverbal stimuli) and postoperative deterioration in verbal learning and verbal recall in 91 patients (48 right, RTL; 43 left, LTL) who had undergone a standard anterior temporal lobe resection for the relief of medically intractable epilepsy and who had been followed up 1 year postoperatively. RESULTS: In the RTL group, the IAP scores were not significant predictors of a postoperative decline in verbal learning or recall. In the LTL group, postoperative decline in verbal learning was associated with good preoperative baseline scores, an older age at the time of surgery, and an unexpected asymmetry on the IAP. Baseline neuropsychological scores and scores from the IAP were associated with a significant postoperative decline in verbal recall in the LTL group. CONCLUSIONS: Scores from the IAP using mixed stimuli were not helpful in the prediction of postoperative verbal memory decline in RTL patients. The significance of IAP scores in predicting verbal memory deficits in LTL patients may be task specific.
Authors: Jeffrey R Binder; David S Sabsevitz; Sara J Swanson; Thomas A Hammeke; Manoj Raghavan; Wade M Mueller Journal: Epilepsia Date: 2008-04-24 Impact factor: 5.864
Authors: Franklin C Brown; Michael Westerveld; John T Langfitt; Marla Hamberger; Hamada Hamid; Shlomo Shinnar; Michael R Sperling; Orrin Devinsky; William Barr; Joseph Tracy; David Masur; Carl W Bazil; Susan S Spencer Journal: Epilepsy Behav Date: 2013-11-26 Impact factor: 2.937
Authors: Nadine Conradi; Friederike Rosenberg; Susanne Knake; Louise Biermann; Anja Haag; Iris Gorny; Anke Hermsen; Viola von Podewils; Marion Behrens; Marianna Gurschi; Richard du Mesnil de Rochemont; Katja Menzler; Sebastian Bauer; Susanne Schubert-Bast; Christopher Nimsky; Jürgen Konczalla; Felix Rosenow; Adam Strzelczyk Journal: Sci Rep Date: 2021-05-26 Impact factor: 4.379