Literature DB >> 17346079

Synthesis of valiolamine and some precursors for bioactive carbaglycosylamines from (-)-vibo-quercitol produced by biogenesis of myo-inositol.

Seiichiro Ogawa1, Miki Kanto.   

Abstract

A convenient and practical synthesis of valiolamine (4) and its related carbaglycosylamine glycosidase inhibitors from (-)-vibo-quercitol (13), a compound readily produced by biogenesis of myo-inositol (9), is described.

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Year:  2007        PMID： 17346079     DOI： 10.1021/np068069t

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  3 in total

1.  Endogenously synthesized (-)-proto-quercitol and glycine betaine are principal compatible solutes of Schizochytrium sp. strain S8 (ATCC 20889) and three new isolates of phylogenetically related thraustochytrids.

Authors:  Anita N Jakobsen; Inga M Aasen; Arne R Strøm
Journal:  Appl Environ Microbiol       Date:  2007-07-27       Impact factor: 4.792

Review 2.  Design and synthesis of biologically active carbaglycosylamines: From glycosidase inhibitors to pharmacological chaperones.

Authors:  Seiichiro Ogawa; Shinichi Kuno; Tatsushi Toyokuni
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2022       Impact factor: 3.945

3.  Chaperone therapy for neuronopathic lysosomal diseases: competitive inhibitors as chemical chaperones for enhancement of mutant enzyme activities.

Authors:  Yoshiyuki Suzuki; Seiichiro Ogawa; Yasubumi Sakakibara
Journal:  Perspect Medicin Chem       Date:  2009-05-26
  3 in total

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