Literature DB >> 17345739

A new consecutive three-component oxazole synthesis by an amidation-coupling-cycloisomerization (ACCI) sequence.

Eugen Merkul1, Thomas J J Müller.   

Abstract

A novel consecutive three-component synthesis of 1-(hetero)-aryl-2-(2-(hetero)aryl-oxazol-5-yl) ethanones starting from propargyl amine and acid chlorides, both for amidation and cross-coupling, is based upon an amidation-coupling-cycloisomerization (ACCI) sequence.

Entities:  

Year:  2006        PMID: 17345739     DOI: 10.1039/b610839c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  4 in total

Review 1.  Transition metal-mediated synthesis of monocyclic aromatic heterocycles.

Authors:  Anton V Gulevich; Alexander S Dudnik; Natalia Chernyak; Vladimir Gevorgyan
Journal:  Chem Rev       Date:  2013-01-10       Impact factor: 60.622

2.  Ugi/Robinson-Gabriel reactions directed toward the synthesis of 2,4,5-trisubstituted oxazoles.

Authors:  Arthur Y Shaw; Zhigang Xu; Christopher Hulme
Journal:  Tetrahedron Lett       Date:  2012-02-13       Impact factor: 2.415

3.  Synthesis of anionic phosphorus-containing heterocycles by intramolecular cyclizations involving N-functionalized phosphinecarboxamides.

Authors:  Thomas P Robinson; Jose M Goicoechea
Journal:  Chemistry       Date:  2015-03-03       Impact factor: 5.236

4.  1,2-Diaryl(3-pyridyl)ethanone oximes. Intermolecular hydrogen bonding networks revealed by X-ray diffraction.

Authors:  Ermitas Alcalde; Neus Mesquida; Carmen Alvarez-Rúa; Rosa Cuberes; Jordi Frigola; Santiago García-Granda
Journal:  Molecules       Date:  2008-02-07       Impact factor: 4.411

  4 in total

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