| Literature DB >> 17344034 |
Alexandra Schosser1, Karoline Fuchs, Theresa Scharl, Friedrich Leisch, Ursula Bailer, Siegfried Kasper, Werner Sieghart, Kurt Hornik, Harald N Aschauer.
Abstract
After publishing a genome scan and follow-up fine mapping, suggesting schizophrenia and bipolar disorder linkage to chromosome 3q29, we now genotyped 11 additional SNPs (single nucleotide polymorphisms), in order to narrow down a potential candidate region. Linkage was performed using the GENEHUNTER program version 2.1r3. A NPL score Z(all) of 3.891 (p=0.000156) was observed with SNP rs225. In short, we found significant linkage scores most telomeric on chromosome 3q29, spanning 3.46 Mbp (7 SNPs).Entities:
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Year: 2007 PMID： 17344034 DOI： 10.1016/j.euroneuro.2007.01.004
Source DB: PubMed Journal: Eur Neuropsychopharmacol ISSN： 0924-977X Impact factor: 4.600