Literature DB >> 17343838

Adiponectin as an anti-inflammatory factor.

Noriyuki Ouchi1, Kenneth Walsh.   

Abstract

Obesity is characterized by low-grade systemic inflammation. Adiponectin is an adipose tissue-derived hormone, which is downregulated in obesity. Adiponectin displays protective actions on the development of various obesity-linked diseases. Several clinical studies demonstrate the inverse relationship between plasma adiponectin levels and several inflammatory markers including C-reactive protein. Adiponectin attenuates inflammatory responses to multiple stimuli by modulating signaling pathways in a variety of cell types. The anti-inflammatory properties of adiponectin may be a major component of its beneficial effects on cardiovascular and metabolic disorders including atherosclerosis and insulin resistance. In this review, we focus on the role of adiponectin in regulation of inflammatory response and discuss its potential as an anti-inflammatory marker.

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Year:  2007        PMID： 17343838      PMCID： PMC2755046          DOI： 10.1016/j.cca.2007.01.026

Source DB:  PubMed          Journal:  Clin Chim Acta        ISSN： 0009-8981            Impact factor:   3.786


  106 in total

1.  Inverse association between adiponectin and C-reactive protein in substantially healthy Japanese men.

Authors:  Kunihiro Matsushita; Hiroshi Yatsuya; Koji Tamakoshi; Keiko Wada; Rei Otsuka; Huiming Zhang; Kaichiro Sugiura; Takahisa Kondo; Toyoaki Murohara; Hideaki Toyoshima
Journal:  Atherosclerosis       Date:  2005-12-01       Impact factor: 5.162

2.  Role of adiponectin receptors in endothelin-induced cellular hypertrophy in cultured cardiomyocytes and their expression in infarcted heart.

Authors:  Daisuke Fujioka; Ken-ichi Kawabata; Yukio Saito; Tsuyoshi Kobayashi; Takamitsu Nakamura; Yasushi Kodama; Hajime Takano; Jyun-ei Obata; Yoshinobu Kitta; Ken Umetani; Kiyotaka Kugiyama
Journal:  Am J Physiol Heart Circ Physiol       Date:  2006-01-13       Impact factor: 4.733

3.  Serum adiponectin, interleukin-10 levels and inflammatory markers in the metabolic syndrome.

Authors:  K M Choi; O H Ryu; K W Lee; H Y Kim; J A Seo; S G Kim; N H Kim; D S Choi; S H Baik
Journal:  Diabetes Res Clin Pract       Date:  2006-07-26       Impact factor: 5.602

4.  Adiponectin and coronary heart disease: a prospective study and meta-analysis.

Authors:  Naveed Sattar; Goya Wannamethee; Nadeem Sarwar; Julia Tchernova; Lynne Cherry; A Michael Wallace; John Danesh; Peter H Whincup
Journal:  Circulation       Date:  2006-08-07       Impact factor: 29.690

5.  Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway.

Authors:  N Ouchi; S Kihara; Y Arita; Y Okamoto; K Maeda; H Kuriyama; K Hotta; M Nishida; M Takahashi; M Muraguchi; Y Ohmoto; T Nakamura; S Yamashita; T Funahashi; Y Matsuzawa
Journal:  Circulation       Date:  2000-09-12       Impact factor: 29.690

6.  Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.

Authors:  K Hotta; T Funahashi; Y Arita; M Takahashi; M Matsuda; Y Okamoto; H Iwahashi; H Kuriyama; N Ouchi; K Maeda; M Nishida; S Kihara; N Sakai; T Nakajima; K Hasegawa; M Muraguchi; Y Ohmoto; T Nakamura; S Yamashita; T Hanafusa; Y Matsuzawa
Journal:  Arterioscler Thromb Vasc Biol       Date:  2000-06       Impact factor: 8.311

7.  Reduction of infarct size by selective stimulation of prostaglandin EP(3)receptors in the reperfused ischemic pig heart.

Authors:  T Hohlfeld; J Meyer-Kirchrath; Y C Vogel; K Schrör
Journal:  J Mol Cell Cardiol       Date:  2000-02       Impact factor: 5.000

8.  Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages.

Authors:  T Yokota; K Oritani; I Takahashi; J Ishikawa; A Matsuyama; N Ouchi; S Kihara; T Funahashi; A J Tenner; Y Tomiyama; Y Matsuzawa
Journal:  Blood       Date:  2000-09-01       Impact factor: 22.113

9.  Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin.

Authors:  N Ouchi; S Kihara; Y Arita; K Maeda; H Kuriyama; Y Okamoto; K Hotta; M Nishida; M Takahashi; T Nakamura; S Yamashita; T Funahashi; Y Matsuzawa
Journal:  Circulation       Date:  1999 Dec 21-28       Impact factor: 29.690

10.  Genomic expression profiling of human inflammatory cardiomyopathy (DCMi) suggests novel therapeutic targets.

Authors:  F Wittchen; L Suckau; H Witt; C Skurk; D Lassner; H Fechner; I Sipo; U Ungethüm; P Ruiz; M Pauschinger; C Tschope; U Rauch; U Kühl; H-P Schultheiss; W Poller
Journal:  J Mol Med (Berl)       Date:  2006-11-15       Impact factor: 4.599
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  221 in total

1.  Sustained release of adiponectin improves osteogenesis around hydroxyapatite implants by suppressing osteoclast activity in ovariectomized rabbits.

Authors:  En Luo; Jing Hu; Chongyun Bao; Yunfeng Li; Qisheng Tu; Dana Murray; Jake Chen
Journal:  Acta Biomater       Date:  2011-10-25       Impact factor: 8.947

2.  APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway.

Authors:  Xiaoban Xin; Lijun Zhou; Caleb M Reyes; Feng Liu; Lily Q Dong
Journal:  Am J Physiol Endocrinol Metab       Date:  2010-10-26       Impact factor: 4.310

3.  Metabolic and neurologic consequences of chronic lopinavir/ritonavir administration to C57BL/6 mice.

Authors:  Paul J Pistell; Sunita Gupta; Alecia G Knight; Michelle Domingue; Romina M Uranga; Donald K Ingram; Indu Kheterpal; Carmen Ruiz; Jeffrey N Keller; Annadora J Bruce-Keller
Journal:  Antiviral Res       Date:  2010-10-21       Impact factor: 5.970

4.  Adiponectin reduces C-reactive protein expression and downregulates STAT3 phosphorylation induced by IL-6 in HepG2 cells.

Authors:  Haiyun Sun; Yingnan Zhang; Ping Gao; Qiang Li; Yuqian Sun; Jinchao Zhang; Changqing Xu
Journal:  Mol Cell Biochem       Date:  2010-10-27       Impact factor: 3.396

5.  Prediagnostic Plasma Adiponectin and Survival among Patients with Colorectal Cancer.

Authors:  Dawn Q Chong; Raaj S Mehta; Mingyang Song; Dmitriy Kedrin; Jeffrey A Meyerhardt; Kimmie Ng; Kana Wu; Charles S Fuchs; Edward L Giovannucci; Shuji Ogino; Andrew T Chan
Journal:  Cancer Prev Res (Phila)       Date:  2015-09-17

6.  Inhibition of pannexin-1 channel activity by adiponectin in podocytes: Role of acid ceramidase activation.

Authors:  Guangbi Li; Qinghua Zhang; Jinni Hong; Joseph K Ritter; Pin-Lan Li
Journal:  Biochim Biophys Acta Mol Cell Biol Lipids       Date:  2018-08-01       Impact factor: 4.698

7.  Effect of Probiotic Soy Milk on Serum Levels of Adiponectin, Inflammatory Mediators, Lipid Profile, and Fasting Blood Glucose Among Patients with Type II Diabetes Mellitus.

Authors:  Sadegh Feizollahzadeh; Reza Ghiasvand; Abbas Rezaei; Hossein Khanahmad; Akram Sadeghi; Mitra Hariri
Journal:  Probiotics Antimicrob Proteins       Date:  2017-03       Impact factor: 4.609

8.  Cognitive impairment following high fat diet consumption is associated with brain inflammation.

Authors:  Paul J Pistell; Christopher D Morrison; Sunita Gupta; Alecia G Knight; Jeffrey N Keller; Donald K Ingram; Annadora J Bruce-Keller
Journal:  J Neuroimmunol       Date:  2009-12-08       Impact factor: 3.478

9.  Caloric restriction stimulates revascularization in response to ischemia via adiponectin-mediated activation of endothelial nitric-oxide synthase.

Authors:  Megumi Kondo; Rei Shibata; Rie Miura; Masayuki Shimano; Kazuhisa Kondo; Ping Li; Taiki Ohashi; Shinji Kihara; Norikazu Maeda; Kenneth Walsh; Noriyuki Ouchi; Toyoaki Murohara
Journal:  J Biol Chem       Date:  2008-11-06       Impact factor: 5.157

Review 10.  Emerging role of leptin in rheumatoid arthritis.

Authors:  G Tian; J-N Liang; Z-Y Wang; D Zhou
Journal:  Clin Exp Immunol       Date:  2014-09       Impact factor: 4.330
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