Leptomeningeal carcinomatosis associated with oesophageal adenocarcinoma: two case reports and review of the literature.

Leptomeningeal carcinomatosis (LC) is a rare complication of solid tumours. We report two cases of leptomeningeal carcinomatosis in patients with oesophageal adenocarcinoma. Diagnosis of LC can be overlooked without a high index of suspicion. Multifocality of symptoms and signs is the hallmark of LC. The combination of cerebrospinal fluid cytology and magnetic resonance imaging has a high diagnostic accuracy. The prognosis remains poor and therefore all therapies are still palliative.