Literature DB >> 17342185

Helping Wingless take flight: how WNT proteins are secreted.

George Hausmann1, Carla Bänziger, Konrad Basler.   

Abstract

How functional WNT proteins are made and how their secretion is regulated is becoming a focal point for the WNT-signalling field. Recently, lipoprotein particles, WNT lipid modifications, the conserved transmembrane protein Wntless (WLS; also known as EVI and SRT) and the retromer complex have been implicated in WNT secretion. Our aim is to synthesize ideas from these new findings for the mechanisms that underlie WNT secretion.

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Year:  2007        PMID： 17342185     DOI： 10.1038/nrm2141

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  52 in total

1.  WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification.

Authors:  Gary S Coombs; Jia Yu; Claire A Canning; Charles A Veltri; Tracy M Covey; Jit K Cheong; Velani Utomo; Nikhil Banerjee; Zong Hong Zhang; Raquel C Jadulco; Gisela P Concepcion; Tim S Bugni; Mary Kay Harper; Ivana Mihalek; C Michael Jones; Chris M Ireland; David M Virshup
Journal:  J Cell Sci       Date:  2010-09-07       Impact factor: 5.285

2.  Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation.

Authors:  Xinjun Zhang; Jose Garcia Abreu; Chika Yokota; Bryan T MacDonald; Sasha Singh; Karla Loureiro Almeida Coburn; Seong-Moon Cheong; Mingzi M Zhang; Qi-Zhuang Ye; Howard C Hang; Hanno Steen; Xi He
Journal:  Cell       Date:  2012-06-22       Impact factor: 41.582

Review 3.  Take the Wnt out of the inflammatory sails: modulatory effects of Wnt in airway diseases.

Authors:  Sebastian Reuter; Hendrik Beckert; Christian Taube
Journal:  Lab Invest       Date:  2015-11-23       Impact factor: 5.662

Review 4.  Progress and renewal in gustation: new insights into taste bud development.

Authors:  Linda A Barlow
Journal:  Development       Date:  2015-11-01       Impact factor: 6.868

5.  Mesenchymal Wnt signaling promotes formation of sternum and thoracic body wall.

Authors:  John Snowball; Manoj Ambalavanan; Bridget Cornett; Richard Lang; Jeffrey Whitsett; Debora Sinner
Journal:  Dev Biol       Date:  2015-02-26       Impact factor: 3.582

Review 6.  A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice.

Authors:  Kevin A Maupin; Casey J Droscha; Bart O Williams
Journal:  Bone Res       Date:  2013-03-29       Impact factor: 13.567

7.  Wnt signal transduction pathways.

Authors:  Yuko Komiya; Raymond Habas
Journal:  Organogenesis       Date:  2008-04       Impact factor: 2.500

8.  Wntless functions in mature osteoblasts to regulate bone mass.

Authors:  Zhendong Zhong; Cassandra R Zylstra-Diegel; Cassie A Schumacher; Jacob J Baker; April C Carpenter; Sujata Rao; Wei Yao; Min Guan; Jill A Helms; Nancy E Lane; Richard A Lang; Bart O Williams
Journal:  Proc Natl Acad Sci U S A       Date:  2012-06-28       Impact factor: 11.205

Review 9.  C. elegans as a model for membrane traffic.

Authors:  Ken Sato; Anne Norris; Miyuki Sato; Barth D Grant
Journal:  WormBook       Date:  2014-04-25

Review 10.  The emerging role of substance P/neurokinin-1 receptor signaling pathways in growth and development of tumor cells.

Authors:  Hossein Javid; Fariba Mohammadi; Elnaz Zahiri; Seyed Isaac Hashemy
Journal:  J Physiol Biochem       Date:  2019-08-01       Impact factor: 4.158
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