Literature DB >> 17341299

SBMLeditor: effective creation of models in the Systems Biology Markup language (SBML).

Nicolas Rodriguez1, Marco Donizelli, Nicolas Le Novère.   

Abstract

BACKGROUND: The need to build a tool to facilitate the quick creation and editing of models encoded in the Systems Biology Markup language (SBML) has been growing with the number of users and the increased complexity of the language. SBMLeditor tries to answer this need by providing a very simple, low level editor of SBML files. Users can create and remove all the necessary bits and pieces of SBML in a controlled way, that maintains the validity of the final SBML file.
RESULTS: SBMLeditor is written in JAVA using JCompneur, a library providing interfaces to easily display an XML document as a tree. This decreases dramatically the development time for a new XML editor. The possibility to include custom dialogs for different tags allows a lot of freedom for the editing and validation of the document. In addition to Xerces, SBMLeditor uses libSBML to check the validity and consistency of SBML files. A graphical equation editor allows an easy manipulation of MathML. SBMLeditor can be used as a module of the Systems Biology Workbench.
CONCLUSION: SBMLeditor contains many improvements compared to a generic XML editor, and allow users to create an SBML model quickly and without syntactic errors.

Entities:  

Mesh:

Year:  2007        PMID: 17341299      PMCID: PMC1831489          DOI: 10.1186/1471-2105-8-79

Source DB:  PubMed          Journal:  BMC Bioinformatics        ISSN: 1471-2105            Impact factor:   3.169


  7 in total

1.  The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models.

Authors:  M Hucka; A Finney; H M Sauro; H Bolouri; J C Doyle; H Kitano; A P Arkin; B J Bornstein; D Bray; A Cornish-Bowden; A A Cuellar; S Dronov; E D Gilles; M Ginkel; V Gor; I I Goryanin; W J Hedley; T C Hodgman; J-H Hofmeyr; P J Hunter; N S Juty; J L Kasberger; A Kremling; U Kummer; N Le Novère; L M Loew; D Lucio; P Mendes; E Minch; E D Mjolsness; Y Nakayama; M R Nelson; P F Nielsen; T Sakurada; J C Schaff; B E Shapiro; T S Shimizu; H D Spence; J Stelling; K Takahashi; M Tomita; J Wagner; J Wang
Journal:  Bioinformatics       Date:  2003-03-01       Impact factor: 6.937

2.  Systems biology markup language: Level 2 and beyond.

Authors:  A Finney; M Hucka
Journal:  Biochem Soc Trans       Date:  2003-12       Impact factor: 5.407

3.  Next generation simulation tools: the Systems Biology Workbench and BioSPICE integration.

Authors:  Herbert M Sauro; Michael Hucka; Andrew Finney; Cameron Wellock; Hamid Bolouri; John Doyle; Hiroaki Kitano
Journal:  OMICS       Date:  2003

4.  Systems Biology Markup Language (SBML) Level 2 Version 5: Structures and Facilities for Model Definitions.

Authors:  Michael Hucka; Frank T Bergmann; Andreas Dräger; Stefan Hoops; Sarah M Keating; Nicolas Le Novère; Chris J Myers; Brett G Olivier; Sven Sahle; James C Schaff; Lucian P Smith; Dagmar Waltemath; Darren J Wilkinson
Journal:  J Integr Bioinform       Date:  2015-09-04

5.  Minimum information requested in the annotation of biochemical models (MIRIAM).

Authors:  Nicolas Le Novère; Andrew Finney; Michael Hucka; Upinder S Bhalla; Fabien Campagne; Julio Collado-Vides; Edmund J Crampin; Matt Halstead; Edda Klipp; Pedro Mendes; Poul Nielsen; Herbert Sauro; Bruce Shapiro; Jacky L Snoep; Hugh D Spence; Barry L Wanner
Journal:  Nat Biotechnol       Date:  2005-12       Impact factor: 54.908

6.  BioModels Database: a free, centralized database of curated, published, quantitative kinetic models of biochemical and cellular systems.

Authors:  Nicolas Le Novère; Benjamin Bornstein; Alexander Broicher; Mélanie Courtot; Marco Donizelli; Harish Dharuri; Lu Li; Herbert Sauro; Maria Schilstra; Bruce Shapiro; Jacky L Snoep; Michael Hucka
Journal:  Nucleic Acids Res       Date:  2006-01-01       Impact factor: 16.971

7.  Model storage, exchange and integration.

Authors:  Nicolas Le Novère
Journal:  BMC Neurosci       Date:  2006-10-30       Impact factor: 3.288

  7 in total
  19 in total

Review 1.  Designing and encoding models for synthetic biology.

Authors:  Lukas Endler; Nicolas Rodriguez; Nick Juty; Vijayalakshmi Chelliah; Camille Laibe; Chen Li; Nicolas Le Novère
Journal:  J R Soc Interface       Date:  2009-04-01       Impact factor: 4.118

Review 2.  Standards and ontologies in computational systems biology.

Authors:  Herbert M Sauro; Frank T Bergmann
Journal:  Essays Biochem       Date:  2008       Impact factor: 8.000

Review 3.  Systems glycobiology: biochemical reaction networks regulating glycan structure and function.

Authors:  Sriram Neelamegham; Gang Liu
Journal:  Glycobiology       Date:  2011-03-24       Impact factor: 4.313

4.  BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models.

Authors:  Chen Li; Marco Donizelli; Nicolas Rodriguez; Harish Dharuri; Lukas Endler; Vijayalakshmi Chelliah; Lu Li; Enuo He; Arnaud Henry; Melanie I Stefan; Jacky L Snoep; Michael Hucka; Nicolas Le Novère; Camille Laibe
Journal:  BMC Syst Biol       Date:  2010-06-29

5.  PINT: Pathways INtegration Tool.

Authors:  Y-T Wang; Y-H Huang; Y-C Chen; C-L Hsu; U-C Yang
Journal:  Nucleic Acids Res       Date:  2010-06-10       Impact factor: 16.971

6.  Revision history aware repositories of computational models of biological systems.

Authors:  Andrew K Miller; Tommy Yu; Randall Britten; Mike T Cooling; James Lawson; Dougal Cowan; Alan Garny; Matt D B Halstead; Peter J Hunter; David P Nickerson; Geo Nunns; Sarala M Wimalaratne; Poul M F Nielsen
Journal:  BMC Bioinformatics       Date:  2011-01-14       Impact factor: 3.169

7.  Integrating systems biology models and biomedical ontologies.

Authors:  Robert Hoehndorf; Michel Dumontier; John H Gennari; Sarala Wimalaratne; Bernard de Bono; Daniel L Cook; Georgios V Gkoutos
Journal:  BMC Syst Biol       Date:  2011-08-11

8.  Intrinsic noise analyzer: a software package for the exploration of stochastic biochemical kinetics using the system size expansion.

Authors:  Philipp Thomas; Hannes Matuschek; Ramon Grima
Journal:  PLoS One       Date:  2012-06-12       Impact factor: 3.240

9.  KEGGconverter: a tool for the in-silico modelling of metabolic networks of the KEGG Pathways database.

Authors:  Konstantinos Moutselos; Ioannis Kanaris; Aristotelis Chatziioannou; Ilias Maglogiannis; Fragiskos N Kolisis
Journal:  BMC Bioinformatics       Date:  2009-10-08       Impact factor: 3.169

10.  SBML-SAT: a systems biology markup language (SBML) based sensitivity analysis tool.

Authors:  Zhike Zi; Yanan Zheng; Ann E Rundell; Edda Klipp
Journal:  BMC Bioinformatics       Date:  2008-08-15       Impact factor: 3.169

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