Literature DB >> 17340668

The chemistry and biology of epothilones--the wheel keeps turning.

Karl-Heinz Altmann1, Bernhard Pfeiffer, Stellios Arseniyadis, Benjamin A Pratt, K C Nicolaou.   

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Year:  2007        PMID： 17340668     DOI： 10.1002/cmdc.200600206

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


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  26 in total

Review 1.  Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.

Authors:  K C Nicolaou; Christopher R H Hale; Christian Nilewski; Heraklidia A Ioannidou
Journal:  Chem Soc Rev       Date:  2012-06-28       Impact factor: 54.564

2.  Design and synthesis of C6-C8 bridged epothilone A.

Authors:  Weiqiang Zhan; Yi Jiang; Peggy J Brodie; David G I Kingston; Dennis C Liotta; James P Snyder
Journal:  Org Lett       Date:  2008-03-21       Impact factor: 6.005

Review 3.  Natural Products in the "Marketplace": Interfacing Synthesis and Biology.

Authors:  Benjamin J Huffman; Ryan A Shenvi
Journal:  J Am Chem Soc       Date:  2019-02-13       Impact factor: 15.419

4.  Site occupancy calibration of taxane pharmacology in live cells and tissues.

Authors:  Javier J Pineda; Miles A Miller; Yuyu Song; Hallie Kuhn; Hannes Mikula; Naren Tallapragada; Ralph Weissleder; Timothy J Mitchison
Journal:  Proc Natl Acad Sci U S A       Date:  2018-11-14       Impact factor: 11.205

5.  C6-C8 bridged epothilones: consequences of installing a conformational lock at the edge of the macrocycle.

Authors:  Weiqiang Zhan; Yi Jiang; Shubhada Sharma; Peggy J Brodie; Susan Bane; David G I Kingston; Dennis C Liotta; James P Snyder
Journal:  Chemistry       Date:  2011-11-30       Impact factor: 5.236

6.  Total synthesis of epothilones B and D: stannane equivalents for beta-keto ester dianions.

Authors:  Gary E Keck; Robert L Giles; Victor J Cee; Carrie A Wager; Tao Yu; Matthew B Kraft
Journal:  J Org Chem       Date:  2008-12-19       Impact factor: 4.354

Review 7.  Natural products: a continuing source of novel drug leads.

Authors:  Gordon M Cragg; David J Newman
Journal:  Biochim Biophys Acta       Date:  2013-02-18

8.  Total synthesis and selective activity of a new class of conformationally restrained epothilones.

Authors:  Mamoun M Alhamadsheh; Shuchi Gupta; Richard A Hudson; Lalith Perera; L M Viranga Tillekeratne
Journal:  Chemistry       Date:  2008       Impact factor: 5.236

Review 9.  Epothilones: tubulin polymerization as a novel target for prostate cancer therapy.

Authors:  James J Lee; W Kevin Kelly
Journal:  Nat Clin Pract Oncol       Date:  2008-12-02

10.  Efficient and selective formation of macrocyclic disubstituted Z alkenes by ring-closing metathesis (RCM) reactions catalyzed by Mo- or W-based monoaryloxide pyrrolide (MAP) complexes: applications to total syntheses of epilachnene, yuzu lactone, ambrettolide, epothilone C, and nakadomarin A.

Authors:  Chenbo Wang; Miao Yu; Andrew F Kyle; Pavol Jakubec; Darren J Dixon; Richard R Schrock; Amir H Hoveyda
Journal:  Chemistry       Date:  2013-01-23       Impact factor: 5.236
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