Primary malignant melanoma of the esophagus with multiple esophageal lesions.

BACKGROUND: A 48-year-old Chinese woman presented with a 2-month history of progressive dysphagia for solids, and (less frequently) liquids. She had minimal weight loss and no family history of cancer. INVESTIGATIONS: Physical examination, conventional esophagogastroduodenoscopy, CT, fluorodeoxyglucose-PET, endoscopic ultrasonography, and histopathologic examination of excised tumor and biopsy specimens. DIAGNOSIS: Primary malignant esophageal melanoma with submucosal infiltration but no distant metastasis. MANAGEMENT: Endoscopic polypectomy followed by near-total esophagectomy with esophagogastric anastomosis.