Literature DB >> 17339579

Assessment: use of epidural steroid injections to treat radicular lumbosacral pain: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology.

Carmel Armon1, Charles E Argoff, Jeffrey Samuels, Misha-Miroslav Backonja.   

Abstract

Based on the available evidence, the Therapeutics and Technology Assessment subcommittee concluded that 1) epidural steroid injections may result in some improvement in radicular lumbosacral pain when assessed between 2 and 6 weeks following the injection, compared to control treatments (Level C, Class I-III evidence). The average magnitude of effect is small and generalizability of the observation is limited by the small number of studies, highly selected patient populations, few techniques and doses, and variable comparison treatments; 2) in general, epidural steroid injection for radicular lumbosacral pain does not impact average impairment of function, need for surgery, or provide long-term pain relief beyond 3 months. Their routine use for these indications is not recommended (Level B, Class I-III evidence); 3) there is insufficient evidence to make any recommendation for the use of epidural steroid injections to treat radicular cervical pain (Level U).

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Year:  2007        PMID: 17339579     DOI: 10.1212/01.wnl.0000256734.34238.e7

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  40 in total

1.  Ethical challenges and interventional pain medicine.

Authors:  Gary J Brenner; Karsten Kueppenbender; Jianren Mao; Jeffrey Spike
Journal:  Curr Pain Headache Rep       Date:  2012-02

Review 2.  The role of image guidance in improving the safety of pain treatment.

Authors:  James P Rathmell; Smith C Manion
Journal:  Curr Pain Headache Rep       Date:  2012-02

Review 3.  Epidural steroid injections.

Authors:  Indy M Wilkinson; Steven P Cohen
Journal:  Curr Pain Headache Rep       Date:  2012-02

4.  A look inside an interdisciplinary spine center at an academic medical center.

Authors:  Joseph J Chen; Robert K Yang
Journal:  Iowa Orthop J       Date:  2008

5.  Activation of GRs-Akt-nNOs-NR2B signaling pathway by second dose GR agonist contributes to exacerbated hyperalgesia in a rat model of radicular pain.

Authors:  Jing Zhang; Wei Zhang; Yu'e Sun; Yue Liu; Lihua Song; Zhengliang Ma; Xiaoping Gu
Journal:  Mol Biol Rep       Date:  2014-02-23       Impact factor: 2.316

6.  Treatment of Neuropathic Pain.

Authors:  Matthew T Mendlik; Tanya J Uritsky
Journal:  Curr Treat Options Neurol       Date:  2015-12       Impact factor: 3.598

7.  Ultrasmall Superparamagnetic Iron Oxide Imaging Identifies Tissue and Nerve Inflammation in Pain Conditions.

Authors:  Shiqian Shen; Weihua Ding; Shihab Ahmed; Ranliang Hu; Arissa Opalacz; Sarah Roth; Zerong You; Gregory R Wotjkiewicz; Grewo Lim; Lucy Chen; Jianren Mao; John W Chen; Yi Zhang
Journal:  Pain Med       Date:  2018-04-01       Impact factor: 3.750

Review 8.  Do Epidural Injections Provide Short- and Long-term Relief for Lumbar Disc Herniation? A Systematic Review.

Authors:  Laxmaiah Manchikanti; Ramsin M Benyamin; Frank J E Falco; Alan D Kaye; Joshua A Hirsch
Journal:  Clin Orthop Relat Res       Date:  2015-06       Impact factor: 4.176

9.  Spinal pain: When is it time for an intervention?

Authors:  Gary M Franklin; John Markman
Journal:  Neurol Clin Pract       Date:  2014-08

10.  Effect of interlaminar epidural steroid injection in acute and subacute pain due to lumbar disk herniation: a randomized comparison of 2 different protocols.

Authors:  I D Gelalis; E Arnaoutoglou; E E Pakos; A N Politis; M Rapti; T A Xenakis; G Papadopoulos
Journal:  Open Orthop J       Date:  2009-12-24
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