| Literature DB >> 17338933 |
Abstract
This article briefly reviews the background of endothelium-dependent vasorelaxation, describes the nitric oxide/cGMP/protein kinase pathway and its role in modulating pulmonary vascular tone and remodeling, and describes three approaches that target the nitric oxide/cGMP pathway in the treatment of patients with pulmonary arterial hypertension.Entities:
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Year: 2007 PMID： 17338933 DOI： 10.1016/j.ccm.2006.12.002
Source DB: PubMed Journal: Clin Chest Med ISSN： 0272-5231 Impact factor: 2.878